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🩺 VitaClaw

222 AI Health Skills for OpenClaw

From blood pressure tracking to tumor board analysis — plug-and-play health intelligence for your AI assistant.

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What is VitaClaw?

VitaClaw is an open-source library of 222 modular health AI skills designed to run inside OpenClaw. Each skill is a self-contained SKILL.md file that gives your AI assistant deep, domain-specific health capabilities — from daily vitals logging to clinical genomics interpretation.

VitaClaw is built on three pillars:

1. Health Memory System — Daily wellness tracking under memory/health/ plus a structured clinical record archive under ~/.openclaw/patients/. Your data lives as plain Markdown files on your machine, versioned by git, owned by you.
2. Modular Skills — 222 self-contained SKILL.md files, each defining its own prompt, tools, and data format. Drop in only what you need, edit freely, extend without limits.
3. Scenario Orchestration — 7 scenario apps (e.g., diabetes-control-hub, hypertension-daily-copilot) that chain multiple skills into end-to-end clinical workflows, from data capture through longitudinal analysis to care recommendations.

Why VitaClaw?

Feature	Generic Health App	VitaClaw
Data ownership	Cloud / vendor lock-in	Local files — you own everything
Customization	Fixed features	Edit anySKILL.md
Clinical depth	Consumer-grade	Research-grade (PubMed, ClinVar, GWAS)
Integration	Siloed	Skills chain together via health-memory
AI model	Single vendor	Any model via OpenClaw (Claude, GPT, Gemini, Llama …)

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Installation

Option A — Git Clone (recommended)

# Clone into OpenClaw shared skills directory
git clone https://github.com/vitaclaw/vitaclaw.git ~/.openclaw/skills/vitaclaw

# Or clone into a workspace
git clone https://github.com/vitaclaw/vitaclaw.git ./skills/vitaclaw

Option B — Cherry-pick individual skills

# Copy only the skills you need
cp -r vitaclaw/skills/blood-pressure-tracker ~/.openclaw/skills/
cp -r vitaclaw/skills/diabetes-control-hub   ~/.openclaw/skills/

No build step, no dependencies, no configuration wizard. OpenClaw automatically discovers SKILL.md files in its skills directories.

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Skills Overview

#	Category	Count	Highlights
1	Health Memory & Infrastructure	2	health-memory, medical-record-organizer — unified data layer for all skills
2	Scenario Applications	7	diabetes-control-hub, hypertension-daily-copilot, mental-wellness-companion
3	Daily Health Tracking	23	blood-pressure-tracker, sleep-analyzer, wearable-analysis-agent, weekly-health-digest
4	Mental Health & Crisis	12	crisis-detection-intervention-ai, adhd-daily-planner, grief-companion
5	Chronic Disease & Treatment	10	chemo-side-effect-tracker, medication-reminder, post-surgery-recovery
6	Biomedical Databases	23	pubmed-database, clinvar-database, kegg-database, uniprot-database
7	Pharmacology & Drug Safety	9	drug-interaction-checker, drug-label-lookup, drugbank-database
8	Clinical Research & Trials	7	trial-eligibility-agent, clinical-trial-protocol-skill, clinical-diagnostic-reasoning
9	Genomics & Variant Interpretation	14	variant-interpretation-acmg, gwas-lookup, gwas-prs
10	Pharmacogenomics	4	pharmgx-reporter, nutrigx_advisor, pharmacogenomics-agent
11	Oncology & Precision Medicine	13	tumor-heterogeneity-agent, digital-twin-clinical-agent, hrd-analysis-agent
12	Hematology & Blood Disorders	8	chip-clonal-hematopoiesis-agent, mpn-progression-monitor-agent, myeloma-mrd-agent
13	Immunoinformatics	4	bio-immunoinformatics-neoantigen-prediction, bio-immunoinformatics-mhc-binding-prediction
14	Liquid Biopsy & ctDNA	8	bio-ctdna-mutation-detection, mrd-edge-detection-agent, liquid-biopsy-analytics-agent
15	ToolUniverse Suite	27	Comprehensive multi-tool research workflows spanning databases, analysis, and reporting
16	Medical NLP & Reports	13	clinical-note-summarization, radgpt-radiology-reporter, checkup-report-interpreter
17	Research & Literature	11	literature-review, deep-research, pubmed-search, knowledge-synthesis
18	Data Science & Visualization	4	statistical-analysis, data-visualization-biomedical, exploratory-data-analysis
19	General Health & Lifestyle	19	tcm-constitution-analyzer, travel-health-analyzer, food-database-query
20	Utilities & Document Processing	5	markitdown, pdf-processing-pro, medical-research-toolkit

Total: 222 skills

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Complete Skill Catalog

1. Health Memory & Infrastructure

Skill	Description
health-memory	Centralized health memory hub — manages daily logs and per-item longitudinal tracking files under memory/health/.
medical-record-organizer	Structured medical record archive — auto-classifies PDFs, scans, and lab reports into a per-patient directory (imaging, labs, pathology, genomics, discharge summaries). Builds navigable INDEX.md with one-line summaries.

2. Scenario Applications

Skill	Description
annual-checkup-advisor	Orchestrates comprehensive annual checkup interpretation by coordinating report parsing, lab interpretation, family history analysis, genetic risk scoring, TCM constitution assessment, and guideline lookup.
caffeine-sleep-advisor	Analyzes the relationship between caffeine consumption and sleep quality by coordinating caffeine tracking, sleep analysis, and trend correlation.
calorie-fitness-manager	Manages daily calorie balance and fitness tracking by coordinating BMR/TDEE calculation, nutrition analysis, food lookup, exercise stats, trend analysis, and SMART goal tracking.
diabetes-control-hub	Manages comprehensive diabetes control by coordinating blood glucose tracking, nutrition analysis, exercise correlation, kidney function monitoring, and complication risk assessment.
hypertension-daily-copilot	Provides comprehensive daily hypertension management by coordinating blood pressure tracking, medication adherence, DASH diet scoring, exercise monitoring, and trend analysis.
mental-wellness-companion	Provides daily mental health support by coordinating PHQ-9/GAD-7 assessment, crisis detection, sleep-mood correlation, exercise prescription, and behavioral activation.
nutrition-supplement-optimizer	Evaluates dietary nutrition gaps and supplement safety by coordinating nutrition analysis, food alternatives, supplement interaction checks, adverse event screening, and effect tracking.

3. Daily Health Tracking

Skill	Description
allergy-manager	Manages allergy profiles including food, environmental, and drug allergies. Tracks reactions, identifies cross-reactivity risks, provides seasonal allergy forecasts, and warns about allergen exposure.
blood-pressure-tracker	Records and classifies blood pressure readings per ACC/AHA 2017 guidelines, detects morning surge, analyzes diurnal variation, and generates monthly statistics.
body-composition-analyzer	Analyzes body composition metrics including body fat percentage, muscle mass, visceral fat, and BMI. Tracks trends and provides training and nutrition recommendations.
breathing-exercise-guide	Provides structured breathing exercise programs for stress relief, sleep improvement, focus enhancement, and anxiety management with step-by-step guided instructions.
caffeine-tracker	Tracks daily caffeine intake from beverages, models residual caffeine using half-life decay (t½=5h).
chronic-condition-monitor	Monitors multiple chronic disease indicators (BP, glucose, HbA1c, lipids, uric acid, creatinine, eGFR, liver function) against Chinese clinical guidelines.
circadian-rhythm-optimizer	Analyzes circadian rhythm patterns, assesses chronotype, provides light exposure protocols, optimizes meal/exercise/sleep timing, and supports jet lag recovery and shift work adaptation.
fitness-analyzer	Analyzes exercise data, identifies workout patterns, assesses fitness progress, and provides personalized training recommendations. Supports correlation with chronic disease data.
google-fit-digest	Analyzes Google Fit exported data including steps, heart rate, sleep, and activity metrics. Generates health digests and trend reports from Google Fit JSON/CSV exports.
health-trend-analyzer	Analyzes health data trends and patterns over time. Correlates medications, symptoms, vital signs, lab results, and other health indicators. Identifies concerning trends, improvements, and provides data-driven insights. Supports interactive HTML visualization reports (ECharts).
hormone-health-tracker	Tracks hormone lab results over time, analyzes trends for thyroid, sex hormones, cortisol, and metabolic markers, and provides lifestyle optimization suggestions.
hydration-tracker	Tracks daily water intake, calculates personalized hydration targets based on body weight, activity level, and weather conditions, and provides reminders.
kidney-function-tracker	Tracks kidney function using CKD-EPI 2021 (race-free) eGFR formula, stages CKD G1-G5, monitors albuminuria categories A1-A3, and calculates eGFR decline rate.
menstrual-cycle-tracker	Tracks menstrual cycles, predicts ovulation and next period, logs symptoms and flow, and provides PMS management suggestions.
nutrition-analyzer	Analyzes nutrition data, identifies dietary patterns, assesses nutritional status, and provides personalized nutrition advice. Supports correlation with exercise, sleep, and chronic disease data.
pregnancy-health-tracker	Provides trimester-specific pregnancy health guidance, tracks prenatal appointments, monitors symptoms, and offers nutrition and exercise recommendations.
sleep-analyzer	Analyzes sleep data to compute efficiency, quality score (0-100), and stage distribution.
stress-management-coach	Assesses stress levels, guides breathing exercises and mindfulness practices, analyzes HRV-based stress data, and provides personalized stress reduction strategies.
tumor-marker-trend	Tumor marker trending — records CEA/CA199/AFP and other markers, supports trend analysis, spike detection, and multi-marker comparison.
tumor-journey-summary	Tumor journey timeline summary (based on patient directory structure + LLM extraction).
wearable-analysis-agent	Analyzes longitudinal wearable sensor data (heart rate, activity, sleep) to detect anomalies and provide personalized health insights.
weekly-health-digest	Aggregates the past 7 days of health data from health-memory into a narrative weekly report with a composite health score (0-100), per-domain summaries, cross-domain correlations, and actionable next-week suggestions.
weightloss-analyzer	Analyzes weight loss data, calculates metabolic rate, tracks energy deficit, manages weight loss phases.

4. Mental Health & Crisis Intervention

Skill	Description
adhd-daily-planner	Time-blind friendly planning, executive function support, and daily structure for ADHD brains. Specializes in realistic time estimation, dopamine-aware task design, and building systems.
crisis-detection-intervention-ai	Detect crisis signals in user content using NLP, mental health sentiment analysis, and safe intervention protocols. Implements suicide ideation detection, automated escalation, and crisis resource routing.
crisis-response-protocol	Handle mental health crisis situations in AI coaching safely. Implements crisis detection, safety protocols, emergency escalation, and suicide prevention features.
grief-companion	Compassionate bereavement support, memorial creation, grief education, and healing journey guidance. Specializes in understanding grief stages, creating meaningful tributes, and supporting healing.
hrv-alexithymia-expert	Heart rate variability biometrics and emotional awareness training.
jungian-psychologist	Expert in Jungian analytical psychology, depth psychology, shadow work, archetypal analysis, dream interpretation, active imagination, addiction/recovery through Jungian lens, and the individuation process.
mental-health-analyzer	Analyzes mental health data, identifies psychological patterns, assesses mental health status, and provides personalized mental health advice. Supports correlation with sleep, exercise, and nutrition data.
modern-drug-rehab-computer	Comprehensive knowledge system for addiction recovery environments, supporting both residential and outpatient (IOP/PHP) patients. Expert in evidence-based treatment modalities (CBT, DBT, MI).
psychologist-analyst	Psychological analysis and counseling support.
recovery-community-moderator	Trauma-informed AI moderator for addiction recovery communities. Applies harm reduction principles, honors 12-step traditions, distinguishes healthy conflict from abuse, detects crisis posts.
speech-pathology-ai	Expert speech-language pathologist specializing in AI-powered speech therapy, phoneme analysis, articulation visualization, voice disorders, fluency intervention, and assistive communication.
occupational-health-analyzer	Analyzes occupational health data, identifies work-related health risks, assesses occupational health status, and provides personalized occupational health advice.

5. Chronic Disease & Treatment Management

Skill	Description
cancer-nutrition-coach	Cancer patient nutrition assessment and diet plan generation (NRS-2002 scoring + LLM nutrition advice).
chemo-side-effect-tracker	Chemotherapy side effect tracking — records side effects per CTCAE v5.0 grading, supports cycle comparison, toxicity trend analysis, and comprehensive toxicity reports.
emergency-card	Generates emergency medical information summary cards for quick access. Extracts key information (allergies, medications, emergencies, implants), supports multi-format output (JSON, text, QR code).
family-health-analyzer	Analyzes family medical history, assesses genetic risk, identifies family health patterns, and provides personalized prevention advice.
follow-up-reminder	Follow-up reminder management tool — supports disease-specific follow-up items, periodic reminders, and completion tracking.
goal-analyzer	Analyzes health goal data, identifies goal patterns, assesses goal progress, and provides personalized goal management advice.
medication-reminder	Manages medication schedules, tracks adherence (doses taken vs. prescribed).
post-surgery-recovery	Post-surgery recovery tracking — records drainage, wound status, pain, activity, and dietary recovery; supports milestone checks and follow-up reminders.
rehabilitation-analyzer	Analyzes rehabilitation training data, identifies recovery patterns, assesses rehabilitation progress, and provides personalized recovery advice.
supplement-manager	Supplement management — manages daily supplement regimens, tracks intake records and adherence, RxNorm interaction checks, and intelligent timing advice.

6. Biomedical Databases

Skill	Description
biorxiv-database	Efficient database search tool for bioRxiv preprint server.
cbioportal-database	Query cBioPortal for cancer genomics data including somatic mutations, copy number alterations, gene expression, and survival data across hundreds of cancer studies.
clinicaltrials-database	Query ClinicalTrials.gov via API v2. Search trials by condition, drug, location, status, or phase. Retrieve trial details by NCT ID for clinical research and patient matching.
clinpgx-database	Access ClinPGx pharmacogenomics data (successor to PharmGKB). Query gene-drug interactions, CPIC guidelines, allele functions, for precision medicine and genotype-guided dosing.
clinvar-database	Query NCBI ClinVar for variant clinical significance. Search by gene/position, interpret pathogenicity classifications, access via E-utilities API or FTP, annotate VCFs.
cosmic-database	Access COSMIC cancer mutation database. Query somatic mutations, Cancer Gene Census, mutational signatures, gene fusions. Requires authentication.
ensembl-database	Query Ensembl genome database REST API for 250+ species. Gene lookups, sequence retrieval, variant analysis, comparative genomics, orthologs, VEP predictions.
fda-database	Query openFDA API for drugs, devices, adverse events, recalls, regulatory submissions (510k, PMA), substance identification (UNII).
gene-database	Query NCBI Gene via E-utilities/Datasets API. Search by symbol/ID, retrieve gene info (RefSeqs, GO, locations, phenotypes), batch lookups.
geo-database	Access NCBI GEO for gene expression/genomics data. Search/download microarray and RNA-seq datasets (GSE, GSM, GPL), retrieve SOFT/Matrix files.
gnomad-database	Query gnomAD for population allele frequencies, variant constraint scores (pLI, LOEUF), and loss-of-function intolerance.
gwas-database	Query NHGRI-EBI GWAS Catalog for SNP-trait associations. Search variants by rs ID, disease/trait, gene, retrieve p-values and summary statistics.
hmdb-database	Access Human Metabolome Database (220K+ metabolites). Search by name/ID/structure, retrieve chemical properties, biomarker data, NMR/MS spectra, pathways.
interpro-database	Query InterPro for protein family, domain, and functional site annotations.
kegg-database	Direct REST API access to KEGG (academic use only).
monarch-database	Query the Monarch Initiative knowledge graph for disease-gene-phenotype associations across species.
openalex-database	Query and analyze scholarly literature using the OpenAlex database.
opentargets-database	Query Open Targets Platform for target-disease associations, drug target discovery, tractability/safety data, genetics/omics evidence, known drugs.
pubchem-database	Query PubChem via PUG-REST API/PubChemPy (110M+ compounds). Search by name/CID/SMILES, retrieve properties, similarity/substructure searches, bioactivity.
pubmed-database	Direct REST API access to PubMed. Advanced Boolean/MeSH queries, E-utilities API, batch processing, citation management.
reactome-database	Query Reactome REST API for pathway analysis, enrichment, gene-pathway mapping, disease pathways, molecular interactions, expression analysis.
string-database	Query STRING API for protein-protein interactions (59M proteins, 20B interactions). Network analysis, GO/KEGG enrichment, interaction discovery, 5000+ species.
uniprot-database	Direct REST API access to UniProt. Protein searches, FASTA retrieval, ID mapping, Swiss-Prot/TrEMBL.

7. Pharmacology & Drug Safety

Skill	Description
drug-adverse-event-query	Query drug adverse reaction reports via openFDA FAERS API (frequency, severity, outcomes).
drug-discovery-search	End-to-end drug discovery platform combining ChEMBL compounds, DrugBank, targets, and FDA labels. Natural language powered by Valyu.
drug-interaction-checker	Check drug-drug interactions (based on RxNorm API + FDA label supplement).
drug-label-lookup	Query drug labels via openFDA API (indications, dosage, warnings, contraindications, adverse reactions, drug interactions).
drug-labels-search	Search FDA drug labels with natural language queries. Official drug information, indications, and safety data via Valyu.
drug-name-resolver	Standardize drug names (generic/brand/development codes) to RxNorm RxCUI and retrieve drug classification information.
drug-photo	Medication photo to personalized PGx dosage card via Claude vision — snap a pill, get genotype-informed guidance.
drugbank-database	Access and analyze comprehensive drug information from DrugBank including drug properties, interactions, targets, pathways, chemical structures, and pharmacology data.
drugbank-search	Search DrugBank comprehensive drug database with natural language queries. Drug mechanisms, interactions, and safety data powered by Valyu.

8. Clinical Research & Trials

Skill	Description
clinical-decision-support	Generate professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings, including patient cohort analyses and treatment recommendation reports. Supports GRADE evidence grading, statistical analysis, biomarker integration.
clinical-diagnostic-reasoning	Identify and counteract cognitive biases in medical decision-making through systematic error analysis and contextual algorithm application.
clinical-trial-protocol-skill	Generate clinical trial protocols for medical devices or drugs.
clinical-trial-search	Search ClinicalTrials.gov clinical trials, supports multi-dimensional filtering by disease, intervention, region, trial status.
clinical-trials-search	Search ClinicalTrials.gov with natural language queries. Find clinical trials, enrollment, and outcomes using Valyu semantic search.
trial-eligibility-agent	Parse trial protocols and patient data to produce criterion-level MET/NOT/UNKNOWN determinations with evidence and gaps for clinical trial screening.
trialgpt-matching	Trial shortlist — AI-driven patient-to-trial matching.

9. Genomics & Variant Interpretation

Skill	Description
bio-clinical-databases-clinvar-lookup	Query ClinVar for variant pathogenicity classifications, review status, and disease associations via REST API or local VCF.
bio-clinical-databases-dbsnp-queries	Query dbSNP for rsID lookups, variant annotations, and cross-references to other databases.
bio-clinical-databases-gnomad-frequencies	Query gnomAD for population allele frequencies to assess variant rarity.
bio-clinical-databases-hla-typing	Call HLA alleles from NGS data using OptiType, HLA-HD, or arcasHLA for immunogenomics applications.
bio-clinical-databases-myvariant-queries	Query myvariant.info API for aggregated variant annotations from multiple databases (ClinVar, gnomAD, dbSNP, COSMIC, etc.).
bio-clinical-databases-polygenic-risk	Calculate polygenic risk scores using PRSice-2, LDpred2, or PRS-CS from GWAS summary statistics.
bio-clinical-databases-somatic-signatures	Extract and analyze mutational signatures from somatic variants using SigProfiler or MutationalPatterns.
bio-clinical-databases-tumor-mutational-burden	Calculate tumor mutational burden from panel or WES data with proper normalization and clinical thresholds.
bio-clinical-databases-variant-prioritization	Filter and prioritize variants by pathogenicity, population frequency, and clinical evidence for rare disease analysis.
gwas-lookup	Federated variant lookup across 9 genomic databases — GWAS Catalog, Open Targets, PheWeb (UKB, FinnGen, BBJ), GTEx, eQTL Catalogue.
gwas-prs	Calculate polygenic risk scores from DTC genetic data using the PGS Catalog.
multi-ancestry-prs-agent	AI-powered multi-ancestry polygenic risk score calculation and optimization for equitable disease risk prediction across diverse global populations.
variant-interpretation-acmg	Classifies genetic variants according to ACMG (American College of Medical Genetics) guidelines.
varcadd-pathogenicity	Variant pathogenicity scoring using CADD and other computational predictors.

10. Pharmacogenomics

Skill	Description
bio-clinical-databases-pharmacogenomics	Query PharmGKB and CPIC for drug-gene interactions, pharmacogenomic annotations, and dosing guidelines.
nutrigx_advisor	Generates personalized nutrition reports from consumer genetic data (23andMe, AncestryDNA). Translates nutritionally-relevant SNPs into dietary and supplementation guidance.
pharmacogenomics-agent	AI-driven pharmacogenomic analysis for precision dosing and adverse event prediction using multi-omics data.
pharmgx-reporter	Pharmacogenomic report from DTC genetic data (23andMe/AncestryDNA) — 12 genes, 31 SNPs, 51 drugs.

11. Oncology & Precision Medicine

Skill	Description
autonomous-oncology-agent	Precision oncology research and treatment recommendation.
cancer-metabolism-agent	AI-powered analysis of cancer metabolic reprogramming including Warburg effect, glutamine addiction, lipid metabolism, and metabolic vulnerabilities for therapeutic targeting.
cellular-senescence-agent	AI-powered analysis of cellular senescence for aging research, cancer therapy response, and senolytic drug development.
chromosomal-instability-agent	AI-powered analysis of chromosomal instability (CIN) signatures for cancer prognosis, immunotherapy response prediction, and therapeutic vulnerability identification.
digital-twin-clinical-agent	AI-powered patient digital twin creation for clinical trial simulation, treatment outcome prediction, and personalized medicine using real-world data and multi-omics integration.
hrd-analysis-agent	AI-powered homologous recombination deficiency (HRD) analysis for PARP inhibitor response prediction using genomic scarring signatures and BRCA pathway assessment.
immune-checkpoint-combination-agent	AI-powered analysis for predicting optimal immune checkpoint inhibitor combinations based on tumor microenvironment, biomarkers, and molecular profiling.
microbiome-cancer-agent	AI-powered analysis of microbiome-cancer interactions including tumor microbiome profiling, immunotherapy response prediction, and microbiome-targeted therapeutic opportunities.
nk-cell-therapy-agent	AI-powered NK cell therapy design for cancer immunotherapy including CAR-NK engineering, memory-like NK generation, and KIR/HLA matching optimization.
precision-oncology-agent	Fuse genomic variants, pathology findings, and clinical context to draft evidence-linked therapy options for tumor board review.
tumor-clonal-evolution-agent	AI-powered analysis of tumor clonal architecture, subclonal dynamics, and evolutionary trajectories from multi-region sequencing and longitudinal liquid biopsy data.
tumor-heterogeneity-agent	AI-powered intratumor heterogeneity analysis for clonal architecture reconstruction, subclonal evolution tracking, and therapy resistance prediction.
tumor-mutational-burden-agent	Calculates and harmonizes Tumor Mutational Burden (TMB) across platforms to predict immunotherapy response.

12. Hematology & Blood Disorders

Skill	Description
bone-marrow-ai-agent	AI-powered bone marrow morphology analysis, cell classification, and hematologic disorder diagnosis using deep learning on aspirate and biopsy images.
chip-clonal-hematopoiesis-agent	AI-powered clonal hematopoiesis of indeterminate potential (CHIP) detection, risk stratification, and cardiovascular/malignancy risk prediction.
coagulation-thrombosis-agent	AI-powered analysis of coagulation disorders, thrombosis risk prediction, anticoagulation management, and platelet function assessment.
cytokine-storm-analysis-agent	AI-powered cytokine release syndrome (CRS) and cytokine storm analysis for prediction, monitoring, and management in immunotherapy and infectious disease.
hemoglobinopathy-analysis-agent	AI-powered analysis of hemoglobin disorders including sickle cell disease, thalassemias, and variant hemoglobins using HPLC, electrophoresis, and molecular data.
mpn-progression-monitor-agent	AI-powered myeloproliferative neoplasm monitoring for disease progression prediction, treatment response tracking, and transformation risk assessment in PV, ET, and myelofibrosis.
mpn-research-assistant	Myeloproliferative neoplasm (MPN) research expertise including JAK2/CALR/MPL mutations, myelofibrosis, polycythemia vera, essential thrombocythemia.
myeloma-mrd-agent	AI-powered minimal residual disease (MRD) analysis for multiple myeloma using next-generation flow cytometry, NGS, and mass spectrometry approaches.

13. Immunoinformatics

Skill	Description
bio-immunoinformatics-epitope-prediction	Predict B-cell and T-cell epitopes using BepiPred, IEDB tools, and structure-based methods for vaccine and antibody design.
bio-immunoinformatics-immunogenicity-scoring	Score and prioritize neoantigens and epitopes for immunogenicity using multi-factor models combining MHC binding, processing, expression, and sequence features.
bio-immunoinformatics-mhc-binding-prediction	Predict peptide-MHC class I and II binding affinity using MHCflurry and NetMHCpan neural network models.
bio-immunoinformatics-neoantigen-prediction	Identify tumor neoantigens from somatic mutations using pVACtools for personalized cancer immunotherapy.

14. Liquid Biopsy & ctDNA

Skill	Description
bio-ctdna-mutation-detection	Detects somatic mutations in circulating tumor DNA using variant callers optimized for low allele fractions with UMI-based error suppression.
bio-liquid-biopsy-pipeline	Cell-free DNA analysis pipeline from plasma sequencing to tumor monitoring.
bio-longitudinal-monitoring	Tracks ctDNA dynamics over time for treatment response monitoring using serial liquid biopsy samples.
bio-methylation-based-detection	Analyzes cfDNA methylation patterns for cancer detection using cfMeDIP-seq or bisulfite sequencing with MethylDackel.
bio-tumor-fraction-estimation	Estimates circulating tumor DNA fraction from shallow whole-genome sequencing using ichorCNA.
ctdna-dynamics-mrd-agent	AI-powered circulating tumor DNA dynamics analysis for molecular residual disease detection, treatment response monitoring, and early relapse prediction.
liquid-biopsy-analytics-agent	Comprehensive analysis of liquid biopsy data (ctDNA, CTCs) for cancer detection, MRD monitoring, and response tracking.
mrd-edge-detection-agent	Ultra-sensitive AI-powered molecular residual disease detection using MRD-EDGE deep learning for sub-0.001% VAF ctDNA detection and early relapse prediction.

15. ToolUniverse Suite

Skill	Description
tooluniverse-adverse-event-detection	Detect and analyze adverse drug event signals using FDA FAERS data, drug labels, disproportionality analysis (PRR, ROR, IC), and biomedical evidence.
tooluniverse-cancer-variant-interpretation	Provide comprehensive clinical interpretation of somatic mutations in cancer.
tooluniverse-clinical-guidelines	Search and retrieve clinical practice guidelines across 12+ authoritative sources including NICE, WHO, ADA, AHA/ACC, NCCN, SIGN, CPIC.
tooluniverse-clinical-trial-design	Strategic clinical trial design feasibility assessment using ToolUniverse.
tooluniverse-clinical-trial-matching	AI-driven patient-to-trial matching for precision medicine and oncology.
tooluniverse-disease-research	Generate comprehensive disease research reports using 100+ ToolUniverse tools.
tooluniverse-drug-drug-interaction	Comprehensive drug-drug interaction (DDI) prediction and risk assessment.
tooluniverse-drug-repurposing	Identify drug repurposing candidates using ToolUniverse for target-based, compound-based, and disease-driven strategies.
tooluniverse-drug-research	Generates comprehensive drug research reports with compound disambiguation, evidence grading, and mandatory completeness sections.
tooluniverse-drug-target-validation	Comprehensive computational validation of drug targets for early-stage drug discovery.
tooluniverse-gwas-drug-discovery	Transform GWAS signals into actionable drug targets and repurposing opportunities.
tooluniverse-gwas-finemapping	Identify and prioritize causal variants at GWAS loci using statistical fine-mapping and locus-to-gene predictions.
tooluniverse-gwas-snp-interpretation	Interpret genetic variants (SNPs) from GWAS studies by aggregating evidence from multiple databases.
tooluniverse-gwas-study-explorer	Compare GWAS studies, perform meta-analyses, and assess replication across cohorts.
tooluniverse-gwas-trait-to-gene	Discover genes associated with diseases and traits using GWAS data from the GWAS Catalog (500,000+ associations) and Open Targets Genetics.
tooluniverse-immune-repertoire-analysis	Comprehensive immune repertoire analysis for T-cell and B-cell receptor sequencing data.
tooluniverse-immunotherapy-response-prediction	Predict patient response to immune checkpoint inhibitors (ICIs) using multi-biomarker integration.
tooluniverse-infectious-disease	Rapid pathogen characterization and drug repurposing analysis for infectious disease outbreaks.
tooluniverse-literature-deep-research	Conduct comprehensive literature research with target disambiguation, evidence grading, and structured theme extraction.
tooluniverse-network-pharmacology	Construct and analyze compound-target-disease networks for drug repurposing, polypharmacology discovery, and systems pharmacology.
tooluniverse-pharmacovigilance	Analyze drug safety signals from FDA adverse event reports, label warnings, and pharmacogenomic data.
tooluniverse-polygenic-risk-score	Build and interpret polygenic risk scores (PRS) for complex diseases using GWAS summary statistics.
tooluniverse-precision-medicine-stratification	Comprehensive patient stratification for precision medicine by integrating genomic, clinical, and therapeutic data.
tooluniverse-precision-oncology	Provide actionable treatment recommendations for cancer patients based on molecular profile.
tooluniverse-rare-disease-diagnosis	Provide differential diagnosis for patients with suspected rare diseases based on phenotype and genetic data.
tooluniverse-variant-analysis	Production-ready VCF processing, variant annotation, mutation analysis, and structural variant (SV/CNV) interpretation.
tooluniverse-variant-interpretation	Systematic clinical variant interpretation from raw variant calls to ACMG-classified recommendations with structural impact analysis.

16. Medical NLP & Reports

Skill	Description
chatehr-clinician-assistant	EHR Chat Assistant for clinical workflows.
checkup-report-interpreter	Health checkup report intelligent interpretation (PDF parsing + LLM abnormality identification and health advice).
clinical-nlp-extractor	Extracts medical entities (Diseases, Medications, Procedures) from unstructured clinical text using regex, rules, or LLM wrappers.
clinical-note-summarization	Structure raw clinical notes into SOAP-format summaries with explicit contradictions, missing data, and ICD-linked assessments.
clinical-reports	Write comprehensive clinical reports including case reports (CARE guidelines), diagnostic reports, clinical trial reports (ICH-E3), and patient documentation (SOAP, H&P, discharge summaries).
lab-results	Lab results interpretation and tracking for healthcare workflows.
medical-entity-extractor	Extract medical entities (symptoms, medications, lab values, diagnoses) from patient messages.
medical-imaging-review	Medical imaging review and analysis.
multimodal-medical-imaging	Analyzes medical images (X-ray, MRI, CT) using multimodal LLMs to identify anomalies and generate reports.
patiently-ai	Simplifies medical documents for patients.
prior-auth-review-skill	Automate payer review of prior authorization (PA) requests.
radgpt-radiology-reporter	Radiology report generation and interpretation.
treatment-plans	Generate concise, focused medical treatment plans in LaTeX/PDF format for all clinical specialties.

17. Research & Literature

Skill	Description
biomedical-search	Complete biomedical information search combining PubMed, preprints, clinical trials, and FDA drug labels. Powered by Valyu semantic search.
citation-management	Comprehensive citation management for academic research.
deep-research	Execute autonomous multi-step deep research on any topic.
knowledge-synthesis	Combines search results from multiple sources into coherent, deduplicated answers with source attribution.
leads-literature-mining	Automated literature review and mining.
literature-review	Conduct comprehensive, systematic literature reviews using multiple academic databases (PubMed, arXiv, bioRxiv, Semantic Scholar, etc.).
literature-search	Comprehensive scientific literature search across PubMed, arXiv, bioRxiv, medRxiv. Natural language queries powered by Valyu semantic search.
medrxiv-search	Search medRxiv medical preprints with natural language queries. Powered by Valyu semantic search.
pubmed-abstract-reader	Batch retrieve PubMed article abstracts, authors, journal details via PMID.
pubmed-search	Intelligent PubMed literature search: 3-layer LLM progressive query + evidence bucketing + stratified sampling for high-quality clinical literature.
research-lookup	Look up current research information using Perplexity's Sonar Pro Search or Sonar Reasoning Pro models through OpenRouter.

18. Data Science & Visualization

Skill	Description
data-stats-analysis	Perform statistical tests, hypothesis testing, correlation analysis, and multiple testing corrections using scipy and statsmodels. Works with ANY LLM provider.
data-visualization-biomedical	Publication-quality visualizations for biomedical and genomics data.
exploratory-data-analysis	Perform comprehensive exploratory data analysis on scientific data files across 200+ file formats.
statistical-analysis	Statistical analysis toolkit. Hypothesis tests (t-test, ANOVA, chi-square), regression, correlation, Bayesian stats, power analysis, assumption checks, APA reporting.

19. General Health & Lifestyle

Skill	Description
care-coordination	Care coordination agent for healthcare workflows.
chronic-pain-manager	Manages chronic pain through pain diary logging, pattern analysis, weather and activity correlation, and non-pharmacological intervention suggestions.
claims-appeals	Claims appeals agent for healthcare workflows.
ehr-fhir-integration	Provides comprehensive tools for working with Electronic Health Records (EHR) using the HL7 FHIR standard.
eye-health-advisor	Provides eye health guidance including 20-20-20 rule reminders, screen time management, vision change tracking, and dry eye prevention tips.
fhir-developer-skill	FHIR development toolkit for healthcare interoperability.
first-aid-guide	Provides step-by-step first aid instructions for common emergencies including burns, fractures, choking, poisoning, and bleeding. Includes CPR guidance.
food-database-query	Comprehensive food nutrition database with search, comparison, recommendations, and automatic calorie calculation.
gut-health-advisor	Assesses gut health through symptom tracking, provides FODMAP dietary guidance, recommends probiotics and prebiotics, and monitors digestive patterns.
longevity-advisor	Provides evidence-based longevity and anti-aging lifestyle recommendations, tracks biological age markers, and synthesizes latest healthspan research.
oral-health-analyzer	Analyzes oral health data, identifies dental issues, assesses oral health status, and provides personalized oral health advice.
posture-ergonomics-coach	Provides posture assessment guidance, workstation ergonomics setup advice, and recommends stretching and strengthening exercises.
sexual-health-analyzer	Comprehensive sexual health data analysis including IIEF-5 scoring, STD screening management, contraception assessment, and cross-domain correlation analysis.
skin-health-analyzer	Analyzes skin health data, identifies skin issues, assesses skin health status, and provides personalized skin health advice.
sleep-optimizer	Generates prioritized, personalized sleep improvement recommendations based on sleep metrics, caffeine data, screen time, and exercise timing.
social-health-tracker	Tracks social interactions, assesses loneliness via UCLA Loneliness Scale, maps Dunbar social circles, generates social health scores, and provides social prescriptions.
tcm-constitution-analyzer	Analyzes TCM (Traditional Chinese Medicine) constitution data, identifies constitution types, assesses characteristics, and provides personalized wellness advice.
travel-health-analyzer	Analyzes travel health data, assesses destination health risks, provides vaccination recommendations, and generates multilingual emergency medical information cards. Integrates WHO/CDC data.
vaccination-tracker	Records vaccination history, tracks due dates for boosters, provides travel vaccination requirements, and maintains an immunization schedule.

20. Utilities & Document Processing

Skill	Description
markitdown	Convert files and office documents to Markdown. Supports PDF, DOCX, PPTX, XLSX, images (with OCR), audio (with transcription), HTML, CSV, JSON, XML, ZIP, YouTube URLs, EPubs and more.
medical-research-toolkit	Query 14+ biomedical databases for drug repurposing, target discovery, clinical trials, and literature research.
pdf	Use this skill for anything with PDF files.
pdf-processing	Extract text and tables from PDF files, fill forms, merge documents.
pdf-processing-pro	Production-ready PDF processing with forms, tables, OCR, validation, and batch operations.

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Scenario Applications

The 7 scenario skills orchestrate multiple sub-skills into complete clinical workflows, turning a single user prompt into a coordinated multi-agent health session.

The diabetes-control-hub scenario illustrates how sub-skills are chained end-to-end:

graph LR
    A[User Input] --> B[chronic-condition-monitor]
    B --> C[nutrition-analyzer]
    C --> D[food-database-query]
    D --> E[fitness-analyzer]
    E --> F[health-trend-analyzer]
    F --> G[health-memory]
    G --> H[Daily Briefing]

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Scenario	What It Coordinates
annual-checkup-advisor	Checkup report parsing, lab interpretation, longitudinal trend analysis, and personalized screening reminders.
caffeine-sleep-advisor	Caffeine intake tracking, sleep quality analysis, circadian rhythm optimization, and behavioral nudge generation.
calorie-fitness-manager	Calorie logging, food database lookup, workout tracking, weight trend analysis, and goal-adjusted meal planning.
diabetes-control-hub	Blood glucose monitoring, nutrition analysis, food database query, fitness tracking, trend analysis, and daily briefing synthesis.
hypertension-daily-copilot	Blood pressure logging, medication adherence tracking, sodium/diet assessment, stress correlation, and alert escalation.
mental-wellness-companion	Mood journaling, sleep quality correlation, stress pattern detection, CBT-aligned suggestions, and weekly wellness summaries.
nutrition-supplement-optimizer	Dietary intake analysis, micronutrient gap detection, supplement interaction checking, and personalized stack recommendations.

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Health Memory System

All VitaClaw health skills share a unified memory layout under memory/health/:

memory/health/
├── _health-profile.md              # Long-term health baseline
├── daily/                           # Daily logs (one file per day)
│   └── YYYY-MM-DD.md
├── items/                           # Per-item longitudinal tracking
│   ├── blood-pressure.md
│   ├── blood-sugar.md
│   └── ...
└── files/                           # Health documents (PDFs, images)

• Daily logs aggregate multi-skill data into one file per day. Each skill writes its own ## Section [skill-name · HH:MM] block.
• Item files maintain 90-day rolling histories for longitudinal metrics (blood pressure, weight, glucose, etc.) with trend summaries.
• Format contract — all skills follow the same Markdown schema with YAML frontmatter, so any skill can consume data produced by any other skill with no transformation needed.

Medical Record Archive

For clinical documents — imaging reports, lab results, pathology, genomics, and discharge summaries — the medical-record-organizer skill provides a structured per-patient archive under ~/.openclaw/patients/:

~/.openclaw/patients/[patient-id]/
├── INDEX.md                  # Navigation entry point
├── profile.json              # Structured patient info
├── timeline.md               # Chronological event table
├── 01_Current Status/
├── 02_Diagnosis & Staging/
├── 03_Molecular Pathology/   # Gene panels + IHC
├── 04_Imaging/               # CT / MRI / PET-CT
├── 05_Lab Results/           # CBC, tumor markers
├── 06_Treatment History/
├── 07_Comorbidities & Meds/
├── 08_Discharge Summaries/
├── 09_Apple_Health/
└── 10_Raw Files/

While health-memory tracks daily wellness metrics (vitals, sleep, nutrition), medical-record-organizer manages clinical documents (hospital reports, scans, lab sheets). Together they form a complete personal health data layer — daily self-tracking plus longitudinal medical records.

See health-memory/SKILL.md for the full specification.

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Medical Disclaimer

VitaClaw is for health management reference only and does not constitute medical diagnosis or treatment advice. Always consult qualified healthcare professionals for medical decisions. In emergencies, call your local emergency number (120/911/999) immediately.

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