MultiVI with Poisson/NB likelihood for ATAC?

[vitkl]

Hi @martinkim0 and all

Similarly to #2249 by @lauradmartens would be great to have a MultiVI version with Poisson or even NB likelihood for ATAC data. How hard do you @martinkim0 think it is to add such option to MultiVI?

[canergen]

Hi @vitkl I'm linking @marianogabitto here as he developed multiVI and was also working on a different implementation of PoissonPeakVI. What's your opinion on this request?

[lauradmartens]

Yes, I also think it should be relatively straightforward and also remember that @marianogabitto already had an implementation

[vitkl]

Thanks for getting back to me about this! If you @marianogabitto have an implementation of this - would be great if you could share it or add it to scvi-tools (if makes sense for @canergen)

[canergen]

Happy to review the PR.

[vitkl]

I don't understand the implementations well enough to easily try implementing this - but I can do a PR if I see the example implementation from @marianogabitto

[canergen]

I'm sorry for the confusion that was a comment to @marianogabitto to assign me the PR if he creates one.

[Juliendly]

Hi all, I am very interested in this implementation and I'm curious to know if there is any updates on it?
Thanks!

[canergen]

@lauradmartens congrats on the new manuscript: https://www.biorxiv.org/content/10.1101/2024.09.19.613754v2. Any plan to continue with the Poisson MultiVI branch.