R2026.3

Issues

• epic: Better Reverse Translation

  app: backendapp: databaseapp: frontendapp: mapperapp: worker
  Epic

  VariantEffect/mavedb-api#746 · Filter by author bencap opened on May 18, 2026 · R2026.3
  

• Redesign stuck-RUNNING-job detection: progress-heartbeat + abort-first recovery

  app: backendapp: worker
  Feature

  VariantEffect/mavedb-api#788 · Filter by author bencap opened on Jul 9, 2026 · R2026.3
  

• Add and maintain a changelog for the Zenodo public data dump

  app: backend
  Task

  VariantEffect/mavedb-api#787 · Filter by author bencap opened on Jul 9, 2026 · R2026.3
  

• Variant search results from superseded score sets

  app: backend
  Bug

  VariantEffect/mavedb-api#776 · Filter by author jstone-dev opened on Jun 23, 2026 · R2026.3
  1

  

• feat: Retroactive backfill — migrate MappedVariant data and run reverse translation for existing score sets

  app: backendapp: worker
  Feature

  VariantEffect/mavedb-api#747 · Filter by author bencap opened on May 18, 2026 · R2026.3
  

• Replace LocalStack with Floci for local S3 emulation

  Task

  VariantEffect/mavedb-api#768 · Filter by author bencap opened on Jun 10, 2026 · R2026.3
  2

  

• Clear existing uniprot_id_from_mapped_metadata value from target_gene prior to updating

  Bug

  VariantEffect/mavedb-api#794 · Filter by author davereinhart opened on Jul 20, 2026 · R2026.3
  

• Unpublished score set deletion often fails.

  app: backend
  Bug

  VariantEffect/mavedb-api#677 · Filter by author jstone-dev opened on Mar 9, 2026 · R2026.3
  

• Mapping fails when a target does not appear in any variants.

  app: worker
  Bug

  VariantEffect/mavedb-api#679 · Filter by author jstone-dev opened on Mar 9, 2026 · R2026.3
  

• Refget sequence endpoint declares the full sequence length as Content-Length on subsequence requests

  app: backend
  Bug

  VariantEffect/mavedb-api#846 · Filter by author bencap opened on Aug 17, 2026 · R2026.3
  

• Add calibration controls to support clinical confidence in variant interpretation

  app: backendapp: databaseapp: frontend
  Epic

  VariantEffect/mavedb-api#754 · Filter by author bencap opened on May 18, 2026 · R2026.3
  

• POST /api/v1/hgvs/validate returns 500 for malformed input

  app: backend
  Bug

  VariantEffect/mavedb-api#860 · Filter by author bencap opened on Aug 28, 2026 · R2026.3
  

• Add pre_mapped_vrs, pre_mapped_vrs_digest, and pre_mapped_vrs_version columns to Variant

  app: backendapp: database
  Feature

  VariantEffect/mavedb-api#867 · Filter by author bencap opened on Sep 15, 2026 · R2026.3

• Mint pre-mapped VRS for non-accession-target variants

  app: backend
  Feature

  VariantEffect/mavedb-api#868 · Filter by author bencap opened on Sep 15, 2026 · R2026.3

• Mint pre-mapped VRS for accession-target variants

  app: backend
  Feature

  VariantEffect/mavedb-api#869 · Filter by author bencap opened on Sep 15, 2026 · R2026.3

• Attach minted pre-mapped VRS to created Variant rows and record the outcome

  app: backend
  Feature

  VariantEffect/mavedb-api#870 · Filter by author bencap opened on Sep 15, 2026 · R2026.3

• Backfill pre-mapped VRS for existing variants

  app: backendapp: database
  Feature

  VariantEffect/mavedb-api#871 · Filter by author bencap opened on Sep 15, 2026 · R2026.3

• Serve pre-mapped VRS through the variant view model and CSV export

  app: backend
  Feature

  VariantEffect/mavedb-api#872 · Filter by author bencap opened on Sep 15, 2026 · R2026.3

• Release 2026.3.0

  core: release
  Unread
  VariantEffect/mavedb-api#907·bencap opened Sep 30, 2026 · Updated Oct 13, 2026
  1