maverefs.tsv

PMID	Journal DOI	Preprint DOI	First Author	Year	Type	Target Molecule	Target Molecule Size (bp)	Variants (nt)	Variants (aa)	Sequence Origin	Assay System	Assay Type	Mutagenesis Type	Sequencing Platform	Raw Data	Scores in Table	MaveDB URN
18045863	10.1074/jbc.M708536200		Barthelemy	2008	DMS	VH domain			180	Human	Phage	Binding	NNS PCR	Illumina			
19915551	10.1038/nbt.1589		Patwardhan	2009	MPRA	T3 promoter;T7 promoter;SP6 promoter;CMV promoter;HBB promoter;S100A4 promoter			12972		in vitro	Transcription	microarray synthesis	Illumina	SRP001721	TXT	
20363230	10.1016/j.jmb.2010.03.058		Dutta	2010	DMS	BH3			170	Human	Yeast	Binding					
20439748	10.1073/pnas.1004290107		Kinney	2010	MPRA	lac promoter			220591		E.coli	FACS	doped oligo synthesis	Roche 454	SRA012345	No	
20711194	10.1038/nmeth.1492		Fowler	2010	DMS	WW domain	102		362000	human	Phage	Binding	doped oligo synthesis	Illumina	SRP002725	No	urn:mavedb:00000002
20714644	10.1039/c0mb00061b		Ernst	2010	DMS	Synthetic PDZ domain			26566		Phage	Binding	Kunkel	Roche 454	No	No	
21464309	10.1073/pnas.1016024108		Hietpas	2011	DMS	Hsp90	27		200	yeast	Yeast	Growth	NNN PCR	Illumina	No	TXT	urn:mavedb:00000011
21825149	10.1073/pnas.1111218108		Zhang	2011	DMS	IgG				Human	Phage	Binding	Combinatorial	Roche 454	No	No	
22325784	10.1016/j.str.2011.11.021		Adkar	2012	DMS	Ccdb	306		1176	E. coli	E.coli	toxin activity	PCR with specific codons	Roche 454	No	XLS	urn:mavedb:00000084
22371081	10.1038/nbt.2136		Patwardhan	2012	MPRA	ALDOB enhancer;ECR11 enhancer;LTV1 enhancer	259;620;302	33411;191890;45499		human	mouse liver	Transcription	doped oligo synthesis	Illumina	SRA049159	TXT	urn:mavedb:00000006;urn:mavedb:00000007;urn:mavedb:00000008
22371084	10.1038/nbt.2137		Melnikov	2012	MPRA	cAMP-regulated enhancer;interferon-B enhancer			27000		Human cell culture (HEK239T)	Transcription	in silico design and synthesis	Illumina	GSE31982	XLS	
22609971	10.1038/nbt.2205		Sharon	2012	MPRA	designed promoters		6500			Yeast	Fluorescence;Transcription	microarray synthesis	Illumina	No	No	
22634563	10.1038/nbt.2214		Whitehead	2012	DMS	Designed influenza binder			1053; 1013		Yeast	FACS	synthesized	Illumina	No	No	
22665811	10.1073/pnas.1202107109		Schlinkmann	2012	DMS	Neurotensin receptor 1 GPCR			6897	Human	E.coli	FACS	NNN PCR	Roche 454	No	No	
22846908	10.1016/j.jmb.2012.07.017		Traxlmayr	2012	DMS	IgG	318			human	Yeast	FACS	error-prone PCR	Roche 454	No	No	urn:mavedb:00000072
23017428	10.1016/j.jmb.2012.09.014		Deng	2012	DMS	TEM1 Beta-lactamase			4997		E.coli	Amp resistance	NNS Kunkel	Roche 454	No	XLS	
23035249	10.1073/pnas.1209751109		Araya	2012	DMS	WW domain					Phage	Binding	doped oligo synthesis	Illumina	Yes	No	
23041932	10.1038/nature11500		McLaughlin	2012	DMS	PSD95 PDZ	249		1578	Human	Bacteria	Special	NNS PCR	Illumina	No	No	urn:mavedb:00000090
23103372	10.1016/j.bbrc.2012.10.066		Fujino	2012	DMS	Fab antibody fragment			950		in vitro	Ribodisplay	PCR with fragments	Roche 454	No	No	
23152521	10.1128/JVI.01658-12		Wu	2012	DMS	Neuraminidase				Influenza	Human/H1N1	Oseltamivir resistance	error prone pcr	Roche 454	No	No	
23241746	10.1101/gr.144659.112		Liachko	2012	MPRA	Autonomously replicating sequences		22000			Yeast	Growth	doped oligo synthesis	Illumina	SRA051406	No	
23287719	10.1126/science.1230161		Ernst	2013	DMS	Ubiquitin					Phage	Binding	site-directed mutagenesis with doped oligos	ELISA	No	No	
23376099	10.1016/j.jmb.2013.01.032		Roscoe	2013	DMS	Ubiquitin	225	4800	1575	yeast	Yeast	Growth	NNN PCR	Illumina	No	XLS	urn:mavedb:00000037
23509263	10.1073/pnas.1303309110		Starita	2013	DMS	E4B	309		98299	human	Phage	Auto-ubiquitination	doped oligo synthesis	Illumina (barcoded and subassembly)	No	XLS	urn:mavedb:00000004
23512712	10.1101/gr.144899.112		Kheradpour	2013	MPRA	Regulatory motifs for HNF1;HNF4;FOXA;GATA;NFE2L2;GFI1;ZFP161		5418			Human cell culture (K562 and HepG2)	Transcription	microarray synthesis	Illumina	GSE33367	TXT	
23625929	10.1074/jbc.M112.447326		Gold	2013	DMS	PKA RII			460	Human	Phage	Binding	doped oligo synthesis	Illumina	No	No	
23765106	10.4161/mabs.24979		Forsyth	2013	DMS	IgG			1060	Human	Human cells	FACS	NNK PCR	Roche 454	No	PDF	
23818646	10.1073/pnas.1307449110		White	2013	MPRA	Crx target sequences		777			Mouse retina	Transcription	microarray synthesis	Illumina	No	TXT	
23825969	10.1371/journal.pgen.1003600		Jiang	2013	DMS	Hsp90	27	576	189	yeast	Yeast	Growth	NNN PCR	Illumina	No	XLS	urn:mavedb:00000039
23827138	10.1016/j.jmb.2013.06.035		Procko	2013	DMS	Designed protein binder			1060	Synthetic (designed)	Yeast	FACS	site-directed mutagenesis and error-prone PCR	Illumina	No	No	
23878237	10.1073/pnas.1215206110		Jacquier	2013	DMS	TEM1 Beta-lactamase			2893	E. coli	E.coli	Amoxicillin resistance	single nucleotide random	Sanger!	No	XLS	
23892608	10.1038/ng.2713		Smith	2013	MPRA	Synthetic liver enhancers			5000		mouse primary liver;human HepG2 cell line	Transcription	designed combinations of binding sites	Illumina	SRP018414	XLS	
23897579	10.1074/mcp.O113.031708		Kim	2013	DMS	Yeast degron			30000	S. cerevisiae	Yeast	Growth	doped oligo synthesis	Illumina	No	No	
23921661	10.1101/gr.157891.113		Mogno	2013	MPRA	Synthetic promoters		2534			Yeast	Transcription	Combinatorial	Illumina	No	TXT	
23924614	10.1073/pnas.1301301110		Kosuri	2013	MPRA	Synthetic promoters and ribosome binding sites			12563		E.coli	Transcription and translation	designed combinations of binding sites	Illumina	No	XLS	
24005320	10.1038/nature12443		Tinberg	2013	DMS	Designed digoxigenin binder			397		Yeast	FACS	doped oligo synthesis	Illumina	No	PDF (Counts)	
24064791	10.1261/rna.040709.113		Melamed	2013	DMS	Pab1	225		110745	human	Yeast	Growth	doped oligo synthesis	Illumina	No	XLS	urn:mavedb:00000010
24112705	10.1111/pcmr.12171		Wagenaar	2013	DMS	BRAF V600E	357		1463	Human	Human	vemurafenib resistance	NNN PCR	Illumina	No	XLS (Partial)	urn:mavedb:00000091
24204297	10.1371/journal.pgen.1003882		Rockah-Shmuel	2012	DMS	M.HaeIII					E.coli	Indel read-through;activity	error-prone PCR	Illumina	No	No	
24299404	10.1111/evo.12207		Hietpas	2013	DMS	Hsp90	27		189	yeast	Yeast	Growth	NNN PCR	Illumina	No	XLS	urn:mavedb:00000040
24381156	10.1073/pnas.1313605111		Strauch	2014	DMS	Designed IgG				Synthetic	Yeast	FACS	error-prone PCR	Illumina	No	No	
24449856	10.1073/pnas.1319402111		Ostermaier	2014	DMS	ARRB1	1209	403	403	human	E. coli	Binding	PCR - Alanine scan	n/a	No	XLS	urn:mavedb:00000082
24567513	10.1093/molbev/msu081		Firnberg	2014	DMS	TEM-1 BL	861		15167	e. coli	Bacteria	Growth	PFunkel	Roche 454	No	XLS	urn:mavedb:00000070
24603708	10.1371/journal.pgen.1004169		Liachko	2014	MPRA	Autonomously replicating sequences		400		P. pastoris	Yeast	Growth	doped oligo synthesis	Illumina	SRP031760	No	
24633241	10.1038/nbt.2851		Zhao	2014	MPRA	3' UTR		2828			Human cell culture (BEAS-2B;Jurkat or WiDr cells)	mRNA stability and protein level	microarray synthesis	Illumina	SRX463338	XLS	
24656821	10.1016/j.celrep.2014.03.001		Oikonomou	2014	MPRA	3' UTR		16332			Human cells (FlpIn293)	FACS	microarray synthesis	Illumina	GSE55396	XLS	
24722365	10.1371/journal.ppat.1004064		Qi	2014	DMS	NS4B			1806		Human cell culture (Huh-7.5.1)	Growth	NNK PCR	Illumina	No	XLS	
24820965	10.1038/srep04942		Wu	2014	DMS	HA			5100	Influenza							
24859245	10.1093/molbev/msu173		Bloom	2014	DMS	influenza nucleoprotein	1494		9980	Influenza	Human/H1N1	viral replication	NNN PCR	Illumina	SRP036064	XLS	urn:mavedb:00000087
24862281	10.1016/j.jmb.2014.05.019		Roscoe	2014	DMS	Ubiquitin	27;225			yeast	Yeast	Binding	NNN PCR	Illumina	No	XLS	urn:mavedb:00000038
24887409	10.1371/journal.pone.0097817		Shin	2014	DMS	flavin mononucleotide binding fluorescent protein			4000		E.coli	Fluorescence	error-prone PCR	Illumina (barcoded)	PRJNA242983	XLS	
24914046	10.1093/nar/gku511		Melnikov	2014	DMS	APH(3')II			4993	E. coli	Bacteria	Growth	microarray synthesis	Illumina	SRP042113	TXT	
24965464	10.1128/JVI.01494-14		Wu	2014	DMS	NS1			1021	Influenza	HEK293T;A549	Growth;Drug Resistance	Error prone PCR	Illumina			
25006036	10.7554/eLife.03300		Thyagarajan	2014	DMS	Hemagglutinin	1692		1000	Influenza	Influenza	Growth	NNN PCR	Illumina	SRP040983	TXT	urn:mavedb:00000092
25030889	10.1101/gr.168773.113		Sharon	2014	MPRA	designed promoters		6500			Yeast	Fluorescence;Transcription	?	Illumina	GSE55346	TXT	
25064858	10.1093/nar/gku689		Gajula	2014	DMS	AID			384	Human	E.coli	Growth	NNS PCR	Illumina	No	PDF (Counts)	
25085423	10.1101/gad.245936.114		Guy	2014	DMS	tRNA			25491		Yeast	FACS	doped oligo synthesis	Illumina	No	XLS	
25141179	10.1038/nature13695		Findlay	2014	DMS	DBR1		4096			Hap1	Growth	CRISPR	Illumina	SRP044126	XLS	
25170020	10.15252/msb.20145136		Noderer	2014	DMS	Start codon efficiency			65536		Mammalian cell culture	FACS	degenrate PCR	Illumina (barcoded)	No	TXT	
25311858	10.1016/j.jmb.2014.09.025		Reich	2015	DMS	BH3			1000	Human	Yeast	FACS	?	Illumina	No	No	
25371431	10.1093/molbev/msu301		Bank	2015	DMS	Hsp90			1015	yeast	Yeast	Growth	NNN PCR	Illumina	No	No	
25451031	10.1016/j.jmb.2014.10.024		Doolan	2015	DMS	PrP			1341	Human	Yeast	FACS	site-directed mutagenesis	PacBio	No	No	
25455030	10.1016/j.cub.2014.09.072		Olson	2014	DMS	GB1			510747	Streptococcus spp	mRNA display	Binding	NNK PCR	Illumina	No	XLS	
25522661	10.1186/s12977-014-0124-6		Al-Mawsawi	2014	DMS	HIV genome			7314		HIV	Growth	error-prone PCR	Illumina	PRJNA259391	XLS	
25559584	10.1038/nmeth.3223		Kitzman	2014	DMS	Gal4 	192		1320	yeast	Yeast	Growth	PALS (array+PCR)	Illumina (barcoded and subassembly)	PRJNA268398	No	urn:mavedb:00000012
25657251	10.1126/science.1257360		Podgornaia	2015	DMS	PhoQ			160000	E. coli	Bacteria	FACS	NNS PCR	Illumina	No	No	
25723163	10.1016/j.cell.2015.01.035		Stiffler	2015	DMS	TEM1 B-lactamase	861		4997	E. coli	E.coli	Growth	NNS PCR	Illumina	No	XLS	urn:mavedb:00000086
25823446	10.1534/genetics.115.175802		Starita	2015	DMS	BRCA1	909				Yeast;Phage	Growth;Binding	microarray synthesis	Illumina (barcoded and subassembly)	No	No*	urn:mavedb:00000003
25875337	10.1371/journal.pgen.1005147		Shalem	2015	MPRA	3' UTR			13000		Yeast	Fluorescence;Transcription	microarray synthesis	Illumina	No	XLS	
26040002	10.1073/pnas.1422285112		Romero	2015	DMS	Bgl2			3083	Streptomyces spp	Bacteria/microfluidic droplets	Activity	error-prone PCR	Illumina	No	No	
26088137	10.1074/jbc.M115.662783		Koenig	2015	DMS	IgG CDR			1092	Synthetic (antibody FAB)	Phage	Binding	NNK PCR	Illumina	No	No	
26132554	10.1371/journal.pgen.1005310		Wu	2015	DMS	Polymerase PA			5280		Influenza	Growth	error-prone PCR	Illumina	PRJNA254185	XLS	
26170332	10.1073/pnas.1511328112		Kretz	2015	DMS	VWF	219		1286		Phage	Binding/cleavage	doped oligo synthesis	Illumina	No	XLS	
26226986	10.1093/molbev/msv167		Doud	2015	DMS	Nucleoproteins	1494			Influenza	Influenza	Growth	NNN PCR	Illumina	SRP056028	TXT	urn:mavedb:00000088
26274323	10.1371/journal.pcbi.1004421		Rockah-Shmuel	2015	DMS	M.HaeIII			1957	H. aegyptus	Bacteria	Activity	error-prone PCR	Illumina	No	XLS	
26296891	10.1074/jbc.M115.676635		Kowalsky	2015	DMS	TNF;PTxS2;TROP2	738;531		3550;4400;4940	Human; B. pertussis; Human	Yeast	FACS	PFunkel	Illumina	No	TXT	
26369947	10.1021/acssynbio.5b00131		Klesmith	2015	DMS	LGK			8000	E.coli	E.coli	Growth	PFunkel	Illumina	No	No	
26424794	10.1074/jbc.M115.684035		Mueller	2015	noncoding	SMN1-7	54			Human	HeLa	Transcription (minigene)	N PCR	Illumina			
26478181	10.1016/j.cell.2015.09.055		Aakre	2015	DMS	ParD			8424	bacteria	Bacteria	Growth	ProxiMax	Illumina	No	No	
26496609	10.1016/j.cell.2015.09.054		Rosenberg	2015	MPRA	Splice sites		2000000		Synthetic (introns/mini-gene)	HEK293	Isoform occurrence	degenrate PCR	Illumina	GSE74070	No	
26576614	10.1101/gr.193789.115		Shen	2016	MPRA	Promoters and enhancers		45670			Mouse retina;mouse cortex	Transcription	capture of existing elements	Illumina	GSM1463994	XLS	
26626484	10.1016/j.molcel.2015.10.029		Vvedenskaya	2015	MPRA	Neuraminidase			16384		Bacteria	Transcription	MASTER	Illumina	SRP057850	XLS	
26637602	10.1128/AEM.03074-15		Jin	2015	DMS	ACD-1					Bacteria	Growth	doped oligo synthesis	Roche 454	PRJEB11657	No	
26656922	10.1016/j.jmb.2015.11.027		Jiang	2016	DMS	neuraminidase (NA)			450		Influenza	Growth	NNN PCR	Illumina	PRJNA272490	XLS	
26689263	10.1038/nmeth.3696		Taylor	2016	DMS	lac repressor			6000	E. coli	Bacteria	Growth	microarray synthesis	Illumina	GSE75009	No	
26716404	10.7554/eLife.09532		Sahoo	2015	DMS	CcdB;DgkA					Bacteria	Growth	NNN PCR	Roche 454	No	No	
26754751	10.1186/s12864-015-2358-7		Wu	2016	DMS	M segment			1881		Influenza	Growth	error-prone PCR	Illumina	PRJNA285135	XLS	
26779844	10.1002/pro.2881		Foight	2016	DMS	CD40;TANK					Bacteria	FACS	NNK PCR	Illumina	No	No	
26824389	10.7554/eLife.12125		Elazar	2016	DMS	Transmembrane segment	69;72;45		800	e coli	Bacteria	Growth	NNS PCR	Illumina	No	XLS (Counts)	urn:mavedb:00000051
26865697	10.1534/g3.116.027904		Hoggard	2016	MPRA	Autonomously replicating sequences					Yeast	Growth	doped oligo synthesis	Illumina	SRP065331	No	
26936925	10.1534/genetics.116.188037		Rich	2016	MPRA	SUL1 promoter	493	29906		yeast	Yeast	Growth	error-prone PCR	Illumina (barcoded and subassembly)	PRJNA273419	XLS	urn:mavedb:00000009
26941320	10.1126/science.aad6881		Winkelman	2016	MPRA	TSS		1000000		E. coli	Bacteria	Transcription	MASTER	Illumina	No	No	
27013733	10.1126/science.aad9195		Jardine	2016	DMS	eOD-GT6 (immunogen)			1160	Syntehtic	Yeast	FACS	NNK PCR	Illumina	No	No	
27068472	10.1016/j.celrep.2016.03.046		Mishra	2016	DMS	Hsp90	696		12400	yeast	Yeast	Growth	NNN PCR	Illumina	No	XLS	urn:mavedb:00000074
27080103	10.1126/science.aaf0965		Puchta	2016	DMS	snoRNA U3			981		yeast	inducible covering allele	doped oligo synthesis	Illumina (barcoded)	GSE77709	TXT (Counts)	
27080104	10.1126/science.aae0568		Li	2016	DMS	tRNA(Arg-CCU)		65000		yeast	yeast	tRNA folding stability	random single nucleotide	Illumina	PRJNA311172	No	
27111525	10.7554/eLife.15802		Mavor	2016	DMS	Ubiquitin			1475	yeast	Yeast	Growth	NNN PCR	Illumina (barcoded)	SRR3194828	No	
27147747	10.1128/JVI.00804-16		Salamango	2016	DMS	env			2800	MLV	293FT	Infection;Fusogenicity;Viral particle incorporation	NNN PCR	Illumina			
27161764	10.1038/ncomms11558		Julien	2016	MPRA	FAS/CD95	63	189		Human	Human	splicing	commercial library cassete ligation	collapsing read pairs	PRJEB13140	XLS	
27162333	10.1073/pnas.1603271113		Vvedenskaya	2016	MPRA	TSS		16000		E. coli	in vitro;E.coli	Transcription	MASTER	Illumina	SRP071742	No	
27173379	10.1016/j.jmb.2016.04.033		Steinberg	2016	DMS	TEM1 Beta-lactamase	858		12815	E. coli	E.coli	Amp resistance	PFunkel	Roche 454	No	XLS	urn:mavedb:00000085
27193686	10.1038/nature17995		Sarkisyan	2016	DMS	GFP	714	56086			Bacteria	Activity	error-prone PCR	Illumina	PRJNA282342.	TXT	urn:mavedb:00000080
27259153	10.1016/j.cell.2016.04.027		Tewhey	2016	MPRA	eQTL peaks		32373			Human cell lines (NA12878;NA19239;HepG22)	Transcription	microarray synthesis	Illumina	GSE75661	XLS	
27259154	10.1016/j.cell.2016.04.048		Ulirsch	2016	MPRA	GWAS peaks					Human cell lines (K562)	Transcription	microarray synthesis	Illumina	No	No	
27271655	10.3390/v8060155		Doud	2016	DMS	Hemagglutinin			10412		Influenza	Growth	NNN PCR	Illumina	PRJNA309339	TXT	
27374328	10.1016/j.cell.2016.05.070		Gamble	2016	DMS	GFP			35000	A. victoria	Yeast	FACS	NNN/VNN PCR	Illumina	No	No	
27391790	10.7554/eLife.16965		Wu	2016	DMS	GB1			160000		mRNA display	Binding	random single nucleotide	Illumina	PRJNA278685	XLS	
27461281	10.1002/anie.201605470		Kobori	2016	DMS	Self-cleaving ribozyme			10296	Oryza sativa	Ribozyme	Transcription (ribozyme cleavage)	Oligo synthesis	Illumina			
27563054	10.1093/molbev/msw182		Tripathi	2016	DMS	CcdB			1664	E. coli	E.coli	Growth	NNK PCR	Illumina	No	No	
27681597	10.1074/jbc.M116.748681		Harris	2016	DMS	TCR				Synthetic (immunogen)	Yeast	FACS	site-directed mutagenesis	?	No	No	
27699856	10.1002/prot.25175		Kowalsky	2016	DMS	dockerin	486;456		2970; 2778	C. thermocellum and C. cellulolyticum	Yeast	FACS	NNN PCR	Illumina	No	TXT	urn:mavedb:00000077
27741319	10.1371/journal.pone.0164296		Gaiotto	2016	DMS	HA			98	S. cerevisiae EBY100	Yeast	Antibody binding	error-prone PCR	Illumina (barcoded)	PRJEB15301	DOC	
27749844	10.1038/ng.3700		Majithia	2016	DMS	PPARG	1515		9595	Human	Human cells	FACS	microarray synthesis	Illumina	No	No	
27760319	10.1016/j.celrep.2016.09.061		Brenan	2016	DMS	Mapk1/Erk2	1080		6810	Human	Human	inhibitor resistance	microarray synthesis	Illumina	No	XLS	
27820858	10.1371/journal.ppat.1005988		Duenas-Decamp	2016	DMS	Env			380	HIV	HIV	Growth					
27898685	10.1371/journal.pgen.1006321		Qiu	2016	DMS	RNAPII trigger loop			600	yeast	Yeast	Growth	site-directed mutagenesis	Illumina	PRJNA340979	No	
27959955	10.1371/journal.ppat.1006114		Haddox	2016	DMS	Env			10000		HIV	Growth	NNN PCR	Illumina	PRJNA320270	TXT	
27974464	10.1074/jbc.M116.764225		van Rosmalen	2017	DMS	Cyclic peptide			200	Synthetic (epitope)	Yeast	FACS	site-directed mutagenesis	Illumina	No	No	
27984726	10.1016/j.cell.2016.11.031		Fernandes	2016	DMS	Tat;Rev		12928			HIV	Growth	NNN PCR	Illumina	E-MTAB-5154	XLS	
28007883	10.1534/genetics.116.196428		Keskin	2017	DMS	Fis1p	81		520	yeast	Yeast	Growth	site-directed mutagenesis	Illumina	10.5061/dryad.j14r5	XLS (Counts)	urn:mavedb:00000076
28009265	10.1016/j.cels.2016.11.004		Kelsic	2016	DMS	infA			4599		Bacteria	Growth	MAGE	amplicon	E-MTAB-4020	TXT	
28024160	10.1038/nmeth.4121		Yartseva	2017	MPRA	mRNA stability					Zebrafish	Transcription	selected RNA sequences	Illumina	SRP090954	No	
28035901	10.7554/eLife.23156		Adams	2016	DMS	scFV antibody					Yeast	Yeast display	Cassette Ligation	Illumina	PRJNA344711	CSV	
28057863	10.1073/pnas.1613231114		Koenig	2017	DMS	IgG			4360	Human	Phage	Binding	NNK PCR	Illumina	No	No	
28137873	10.1073/pnas.1621150114		Grossman	2017	MPRA	natural and synthetic enhancers					mouse	Transcription	microarray synthesis	Illumina (barcoded)	GSE84888	No	
28196882	10.1073/pnas.1614437114		Klesmith	2017	DMS	TEM-1 BL;LGK			12874	E. colo	Yeast;Bacteria	FACS;Growth	NNN PCR	Illumina	No	No	
28204611	10.1093/nar/gkw942		Maricque	2017	MPRA	genomic regions					Human cells	Transcription	microarray synthesis	Illumina	No	No	
28212748	10.1016/j.molcel.2017.01.007		Levo	2017	MPRA	yeast promoters		1600			Yeast	Transcription	microarray synthesis	Illumina	GSE92300	XLS	
28262665	10.1038/ncomms14614		Chan	2017	DMS	IGPS			5040	bacteria	Yeast	Growth	NNN PCR	Illumina	No	No	
28288189	10.1371/journal.ppat.1006271		Doud	2017	DMS	HA			10000		Influenza	Antibody binding	NNN PCR	Illumina	SAMN05789126	TXT	
28335006	10.1093/nar/gkx183		Matreyek	2017	DMS	GFP N-terminal codon	3				Human cell lines (HEK293T)	FACS	oligo synthesis	Illumina (barcoded)	SRP095490	TXT	urn:mavedb:00000042
28346537	10.1371/journal.ppat.1006288		Ashenberg	2017	DMS	NP	1494			Influenza	Virus	Growth	NNN PCR	Illumina	SRP082554	TXT	urn:mavedb:00000089
28579254	10.1016/j.chom.2017.05.003		Dingens	2017	DMS	Env			12559		HIV	Antibody binding	NNN PCR	Illumina (barcoded)	SRA: SRX2548567-SRX2548579	TXT	
28585537	10.1038/ncomms15695		Wrenbeck	2017	DMS	amiE			42966		E.coli	Growth	Pfunkel	Illumina	PRJNA360623	TXT	
28585908	10.1080/19420862.2017.1337618		Koenig	2017	DMS	IgG heavy chain			640		Phage	Binding	NNK PCR	Illumina (barcoded)	No	PDF	
28618270	10.1016/j.chom.2017.05.011		Wu	2017	DMS	HA RBS			15679		Human cells	Growth	NNK PCR	amplicon	PRJNA353496	XLS	
28652265	10.1158/1541-7786.MCR-17-0245		Bhagavatula	2017	DMS	TP53 synonymous			16916	Human	HEK293T	FACS	doped oligo synthesis	Illumina	PRJNA384242	No	
28686159	10.7554/eLife.27810		Bandaru	2017	DMS	Ras	495		3119	human	Bacteria	activity	NNS PCR	Illumina	No	XLS	urn:mavedb:00000057
28902834	10.1038/nature23902		Starr	2017	DMS	ancestral RH			160000	Human (ancestrally reconstructed protein)	Yeast	FACS	NNK PCR	Illumina	PRJNA362734	No	
29039417	10.1038/nmeth.4464		Woodsmith	2017	DMS	BBSome	2040		1036		yeast	Y2H	PALS (array+PCR)	simple deep sequencing	PRJNA407860	XLS	
29078326	10.1073/pnas.1708268114		Ma	2017	DMS	BCR-ABL			180	Human (ongenic fusion)	Ba/F3 cells	Growth	CRISPR	Illumina	No	No	
29097404	10.1101/gr.224964.117		Cuperus	2017	MPRA	5' UTR			500000	Random sequence	yeast	Growth	random oligos	Illumina	GSE104252	XLS	
29203891	10.1038/s41598-017-17081-y		Spencer	2017	DMS	Cas9	4173		3248	S. pyogenes	Bacteria	Growth	error-prone PCR	Illumina	SRP107783	XLS	urn:mavedb:00000071
29225039	10.1016/j.molcel.2017.11.014		Rabani	2017	MPRA	3' UTR		85500			Zebrafish	Transcript abundance	known UTRs	Illumina	GSE106677	XLS	
29242188	10.1101/gr.219683.116		Ke	2017	MPRA	DHFR exon 1-5	51	5560		human	HEK293	splicing	microarray synthesis	Illumina	GSE105785	XLS	urn:mavedb:00000083
29269382	10.15252/msb.20177908		Weile	2017	DMS	UBE2I;SUMO1;TPK1;CALM1-3	477;306;585;450		13000	human	yeast	complementation	popcode	Barseq+TileSeq (Illumina)	PRJNA390305	TXT	urn:mavedb:00000001
29301959	10.1126/science.aao5167		Plesa	2018	DMS	PPAT			1152		E.coli	Growth	ortholog synthesis	Illumina	SRP126669	XLS	
29410437	10.1038/s41467-018-02980-z		Vainberg Slutskin	2018	MPRA	microRNA		14000		Synthetic	K562	FACS	microarray synthesis	Illumina	SRP128656	No	
29466705	10.1016/j.jmb.2018.02.009		Canale	2018	DMS	HA			254		Human/infulenza	viral replication	?	Illumina	No	XLS (Counts)	
29525204	10.1016/j.cels.2018.01.015		Staller	2018	DMS	Gcn4	132;132		6340	yeast	Yeast	FACS	microarray synthesis	Illumina	10.17632/rbfr6m4733.1	TXT	urn:mavedb:00000052
29590010	10.7554/eLife.34420		Haddox	2018	DMS	Env			28080	HIV (two different variants)	Human/HIV	viral replication	NNN PCR	Illumina (barcoded)	PRJNA371844;PRJNA412552	CSV (Counts)	
29638215	10.7554/eLife.32472		Diss	2018	DMS	AP-1	96;96		120000		Yeast	Growth	doped oligo synthesis	Illumina	GSE102901	XLS	
29643335	10.1038/s41467-018-03783-y		Hartman	2018	DMS	MS2 phage capsid			2580	Phage	MS2	SyMAPS	NNN PCR	Illumina	No	XLS	
29643370	10.1038/s41467-018-03665-3		Doud	2018	DMS	H1 hemaglutinin			10735		Influenza	Growth	NNN PCR	Illumina	SAMN05789126	TXT	
29663315	10.1002/bit.26706		Medina-Cucurella	2018	DMS	canine nerve growth factor		1737			Yeast	Antibody binding by FACS	Pfunkel	Illumina	SRA (SAMN07693504-SAMN07693526)	TSV	
29678950	10.4049/jimmunol.1800343		Heredia	2018	DMS	CXCR4;CCR5	1053;1053		7000	human	Expi293F	FACS;Binding	?	Illumina	GSE100368	XLS	urn:mavedb:00000047;urn:mavedb:00000048
29706350	10.1016/j.ajhg.2018.03.018		Mighell	2018	DMS	PTEN	1212		7244	human	Yeast	lipid phosphatase activity	MITE	Illumina	SRP134135	XLS	urn:mavedb:00000054
29728462	10.1073/pnas.1722055115		Belliveau	2018	MPRA	lacZYA;relBE;marRAB;yebG;purT;xylE;dgoRKADT promoters				E. coli	E.coli	FACS	Cassette Ligation	Illumina	SRP121362	CSV	
29785012	10.1038/s41588-018-0122-z		Matreyek	2018	DMS	PTEN;TPMT	1212;738		7801	human	human	Protein stability	inverse PCR	Illumina (barcoded and subassembly)	PRJNA428380	XLS	urn:mavedb:00000013
29813059	10.1371/journal.pgen.1007419		Dandage	2018	DMS	GmR			2000		E.coli	Gentamicin resistance	NNK PCR	Illumina (barcoded)	PRJNA384918	XLS	
29912470	10.1093/nar/gky255		Atkinson	2018	DMS	adenylate kinase				Not a DMS	E.coli	activity	Transposon mutagenesis (not substitution)	Illumina	SRR6327683;SRR6327684	No	
29931269	10.1093/nar/gky550		Mason	2018	DMS	CDR			14842		PnP hybridoma cells	FACS	CRISPR	Illumina	No	No	
29975771	10.1371/journal.ppat.1007159		Dingens	2018	DMS	env			12730	HIV-1	SupT1.CCR5	Antibody escape	NNN PCR	Ilumina			
29979580	10.1021/acssynbio.8b00121		Scott	2018	DMS	tetracycline inactivating enzyme			7400	E. Coli	Yeast	Tetracycline resistance	error-prone PCR	Illumina	No	No	
29979965	10.1016/j.molcel.2018.06.012		Kotler	2018	DMS	TP53	573		3874	human	HEK293T	Growth	microarray synthesis	Illumina	GSE115072	XLS	urn:mavedb:00000059
30012625	10.1073/pnas.1803598115		Cantor	2018	DMS	EGFR			2600	Human	E.coli	FACS	NNS PCR	Illumina	No	No	
30024376	10.7554/eLife.34300		Salinas	2018	DMS	PDZ			57549	Human	Bacteria	activity	NNS PCR	Illumina	No	No	
30037883	10.1242/bio.036103		Mavor	2018	DMS	Ubiquitin			1520	Yeast	Yeast	Growth	NNN PCR	Illumina (barcoded)	SRP070953	No	
30068600	10.1073/pnas.1805882115		Dorrity	2018	DMS	Ste12			20000	Yeast	Yeast	Mating/Invasion	doped oligo synthesis	Illumina	PRJNA379449	XLS	
30078555	10.1016/j.stemcr.2018.07.002		Veerapandian	2018	DMS	Sox17;Sox2			8000	Mouse	OG2-MEF	FACS	NNK PCR	Illumina			
30079747	10.1164/rccm.201802-0337OC		Castaldi	2019	MPRA	FAM13A locus			45	Human	human; cell line	Transcription	microarray synthesis	Illumina	No	No	
30104379	10.1073/pnas.1806133115		Lee	2018	DMS	HA			10754		Virus	Growth	NNN PCR	Illumina	SAMN08102609;SAMN08102610	TXT	
30120239	10.1038/s41467-018-05748-7		Braun	2018	noncoding	RON exon 11	680	5200		Human	HEK293T	Transcription (minigene splicing)	Error prone PCR	Illumina (barcoded)			
30174293	10.1016/j.molcel.2018.07.033		Wong	2018	MPRA	Splice sites		32768			HeLa	Transcription	?	Illumina	SRP135892	No	
30188321	10.7554/eLife.38795		Phillips	2018	DMS	HA			36790		Influenza	Growth	NNN PCR	Illumina	SRP149672	TXT	
30209399	10.1038/s41586-018-0461-z		Findlay	2018	DMS	BRCA1	647		3893	Human	HAP1	Growth	microarray synthesis + CRISPR	Illumina	No	XLS	urn:mavedb:00000097
30219179	10.1016/j.ajhg.2018.07.016		Starita	2018	DMS	BRCA1	5589		1056	human	human	DNA-repair assay	NNK PCR	Illumina	GSE116427	XLS	urn:mavedb:00000081
30224458	10.1073/pnas.1811993115		Blaesi	2018	DMS	RNR			380	Bacteria	Bacteria	Growth	NNS PCR	Illumina	No	No	
30224644	10.1038/s41588-018-0204-y		Giacomelli	2018	DMS	TP53	1182		25217	human	human	Growth	microarray synthesis	Illumina	No	XLS	urn:mavedb:00000068
30227960	10.1016/j.isci.2018.02.005		Gong	2018	DMS	env			3849	Zika	C6/36;A549;hCMEC/D3	Growth	Error prone PCR	Illumina			
30258049	10.1038/s41467-018-06403-x		Naftaly	2018	DMS	APPI			340	Human	Yeast	FACS	NNS PCR	Illumina	No	No	
30478237	10.15252/msb.20188371		Bassalo	2018	DMS	Lysine metabolic pathway			16300		Bacteria	Growth	microarray synthesis	Illumina	No	XLS	
30503770	10.1016/j.molcel.2018.10.037		Cheung	2019	MPRA	Splice sites			2198	Human	human cells	FACS	microarray synthesis	Illumina	GSE120695	No	
30709739	10.1016/j.immuni.2018.12.017		Dingens	2019	DMS	Env				HIV	HIV	Antibody binding	NNN PCR	Illumina (barcoded)	SRP15794;PRJNA486029	CSV	
30716072	10.1371/journal.pcbi.1006226		Barnes	2019	MPRA	LacI binding site					E.coli	FACS	Cassette Ligation	Illumina	SRP146291	CSV	
30721031	10.1021/acssynbio.8b00486		Wrenbeck	2019	DMS	pyrrolidine ketide synthase;levoglucosan kinase	1143				E.coli	VAMP-seq	NNN;NNK PCR	Illumina	SUB4818031	CSV	urn:mavedb:00000079
30723160	10.1074/jbc.RA118.006173		Park	2020	DMS	T1R2			16300		Expi293F	FACS;surface expression	error-prone PCR	Illumina	GSE115751	XLS	
30761651	10.1002/jmr.2778		Wollacott	2019	DMS	Proliferation-inducing ligand	144		960	Human	Yeast	Binding by FACS	NNK PCR	Illumina	No	No	
30778069	10.1038/s41467-019-08777-y		Michaels	2019	MPRA	microRNA					HEK293T	polysome profiling	degenerate oligos	Illumina	PRJNA516224	No	
30886357	10.1038/s41564-019-0399-4		Setoh	2019	DMS	Zika envelope			3827	Zika	Zika	viral replication	NNN PCR	Illumina (barcoded)	PRJNA449413	CSV	
30894475	10.1128/JVI.00219-19		Heredia	2019	DMS	Env			16332	HIV-1B	Expi293F	Binding by FACS	overlap extension PCR	Illumina (barcoded)	GSE102276;GSE117328;GSE126136	XLS	
30908907	10.1021/acssynbio.8b00529		McGeachy	2019	DMS	RPL28			270000	Yeast	Yeast						
30936490	10.1038/s41564-019-0412-y		Noda-Garcia	2019	DMS	GDH (GudB)			269	Bacillus subtilis	Bacillus subtilis	Growth	NNS PCR	Illumina	No	XLS	
30956043	10.1016/j.molcel.2019.02.003		Ahler	2019	DMS	Src	54;750		3506	human	Yeast	Growth	NNK PCR	Illumina (barcoded and subassembly)	GSE114098	XLS	urn:mavedb:00000041
30969963	10.1371/journal.pgen.1008079		Pokusaeva	2019	DMS	IGPD			48198		Yeast	Growth	?	Illumina	GSE99990	TXT	
30977563	10.1002/humu.23762		Wan	2019	DMS	rhodopsin	1047		210	Human	HEK293T	FACS;surface expression	site-directed mutagenesis	Illumina	No	XLS	urn:mavedb:00000099
31019050	10.1128/JVI.00161-19		Hom	2019	DMS	matrix protein			5040	Influenza	Human/influenza A	viral replication	NNN PCR	Illumina (barcoded)	SRP144482	CSV	
31034887	10.1016/j.jmb.2019.04.030		Gonzalez	2019	DMS	TEM-1	861		4737							XLSX	urn:mavedb:00000100
31038123	10.7554/eLife.45079		Soh	2019	DMS	PB2			15180	Influenza	Influenza	viral replication	NNN PCR	Illumina (barcoded)	PRJNA511556	CSV	
31081325	10.1021/acssynbio.9b00104		Nikoomanzar	2019	DMS	Kod DNA polymerase			940	T kodakarensis	E.coli	activity by DrOPS	site-directed mutagenesis	Illumina	No	No	
31096572	10.3390/v11050439		Dingens	2019	DMS	env			12730	HIV-1		Growth					
31242389	10.1021/acs.molpharmaceut.9b00418		Klesmith	2019	DMS	CD19	816			Synthetic	Yeast	Binding by FACS	NNK PCR	Illumina	No	No	
31267113	10.1038/s41587-019-0164-5		Sample	2019	MPRA	5' UTR		280000		Random	human cells	polysome profiling	random bases	Illumina	GSE114002	No	
31325330	10.1002/prot.25786		Warszawski	2020	DMS	basigin	405		970		Yeast	Binding;expression	NNS PCR	Illumina (barcoded)	No	XLS	
31371509	10.1073/pnas.1903888116		Nisthal	2019	DMS	GB1			1064	Streptococcus							
31395785	10.1126/science.aax3649		Boettcher	2019	DMS	TP53			7893	Human	K562;MOLM13				No	No	
31395865	10.1038/s41467-019-11526-w		Kircher	2019	MPRA	Multiple mammalian promoters and enhancers	600;303;600;385;187;274;285;451;601;318;591;600;463;470;470;600;600;601;600;259;259;259;259;591;579;486;486	30000		human	multiple cell lines	Transcription	error-prone PCR	Illumina	GSE126550	TXT	urn:mavedb:00000014;urn:mavedb:00000015;urn:mavedb:00000016;urn:mavedb:00000017;urn:mavedb:00000018;urn:mavedb:00000019;urn:mavedb:00000020;urn:mavedb:00000021;urn:mavedb:00000022;urn:mavedb:00000023;urn:mavedb:00000024;urn:mavedb:00000025;urn:mavedb:00000026;urn:mavedb:00000027;urn:mavedb:00000028;urn:mavedb:00000029;urn:mavedb:00000030;urn:mavedb:00000031;urn:mavedb:00000032;urn:mavedb:00000033;urn:mavedb:00000034
31400199	10.1093/molbev/msz184		Faber	2019	DMS	AmiE			6407;6791	Pseudomonas aeruginosa	E.coli	Growth	Pfunkel	Illumina (barcoded)	SRA SAMN11258744-SAMN11258771	XLS	
31442220	10.1371/journal.pcbi.1007207		Warszawski	2019	DMS	IgG Fv targeting lysozyme			8505	Human	Yeast	Binding;expression	NNS PCR	Illumina (barcoded)	https://www.addgene.org/110212/	XLS	
31452511	10.7554/eLife.49324		Lee	2019	DMS	HA						Antibody escape					
31467279	10.1038/s41467-019-11735-3		Li	2019	DMS	CI			531								
31511387	10.1128/JVI.01291-19		Sourisseau	2019	DMS	Zika envelope	1512		9576	Zika	Human/Zika	viral replication	NNN PCR	Illumina (barcoded)	PRJNA530795	XLS	urn:mavedb:00000075
31519910	10.1038/s41467-019-12101-z		Bolognesi	2019	DMS	TDP-43	1242		57996	human	Yeast	Toxicity	doped oligo synthesis	Illumina	No		urn:mavedb:00000060
31530582	10.1101/gr.247312.118		Vainberg Slutskin	2019	MPRA	PAS (poly-adenylation site)			12339	HIV1;SVL	K562	Expression					
31558564	10.1534/g3.119.400535		Gray	2019	DMS	amyloid beta 42	126		791	human	Yeast	Growth	NNK PCR	Illumina	GSE139122	TSV	urn:mavedb:00000058
31609039	10.15252/embj.2019102145		Kennouche	2019	DMS	PilE			1147	Neisseria meningitidis							
31665623	10.1016/j.celrep.2019.09.057		Salamango	2019	DMS	HIV-1 Vif			3400	HIV	Human cells	Enzymatic activity	error-prone PCR	Illumina	E-MTAB-8357	No	
31666291	10.1534/genetics.119.302601		Adney	2019	DMS	LINE-1			538	Human							
31697803	10.1182/blood.2019002561		Bridgford	2020	DMS	MPL	93		580	human	Ba/F3 cells	Growth	NNN PCR	Illumina	SRR10193506	TXT	urn:mavedb:00000043
31780559	10.1126/science.aaw2900		Ogden	2019	DMS	AAV2 capsid			29400	AAV	AAV	Production fitness;Infectivity;Thermostability;Antibody neutralization	Oligo synthesis	Illumina			
31796585	10.1073/pnas.1915562116		McShan	2019	DMS	HLA-A*02:01	362		3524	Human	Expi293F	FACS	NNN PCR	Illumina			
31808666	10.1021/acschembio.9b00669		Zinkus-Boltz	2019	DMS	RAF	117				E.coli	Binding	error-prone PCR	Illumina	No	XLS	urn:mavedb:00000061
31905288	10.1021/acs.jcim.9b00954		Nutschel	2020	DMS	LipA			3439	Bacillus subtilis							
31925410	10.1038/s41594-019-0358-z		Persky	2020	DMS	CDK4;CDK6			6060;6520	Human	Human cells	Growth	MITE	?	PRJNA559517	XLS	
31928070	10.1161/CIRCGEN.119.002786	10.1101/773887	Glazer	2019	DMS	SCN5A	36		248	Human							urn:mavedb:00000098
32000841	10.1186/s13073-020-0711-1		Sun	2020	DMS	CBS	1656	10323	6879	human	Yeast	Growth	popcode	Illumina			urn:mavedb:00000005
32004414	10.1111/cts.12758		Zhang	2020	DMS	CYP2C9;CYP2C19	1461;1443	109;121	109;121	human	HEK293T	VAMP-seq	Nicking mutagenesis	Illumina	No	DOC	urn:mavedb:00000062
32094176	10.1073/pnas.1915680117		Suiter	2020	DMS	NUDT15	495		3097	human	HEK293T	VAMP-seq;drug sensitivity	Synthesized	Illumina	No	XLS	urn:mavedb:00000055
32094176	10.1073/pnas.1915680117		Yang	2020	DMS	NUDT15	489		2935	Human	HEK293T	Growth;Flow Cytometry	Twist	Illumina (barcoded)			
32098152	10.3390/v12020241		Roop	2020	DMS	env			12559	HIV-1	Macaque						
32129763	10.7554/eLife.53810		Flynn	2020	DMS	Hsp90			14570	Yeast	Yeast	Growth					
32144244	10.1038/s41467-020-15102-5		Wu	2020	DMS	HA			576	human Influenza H3N2	Influenza	Growth	PCR targeted mutagenesis	Illumina	PRJNA563320	XLS	
32152544	10.1038/s41589-020-0480-6		Newberry	2020	DMS	alpha-synuclein	420		2600	Human	Yeast	Growth	Provided	Illumina (barcoded)	PRJNA564806	XLS	
32175691	10.15252/msb.20199265		Choudhury	2020	DMS	rpoB				E. coli	E.coli	Rifampicin resistance	error-prone PCR	Miseq	GSE143629	CSV	
32181350	10.1126/sciadv.aay7505		Penn	2020	DMS	rhodopsin			808	Human	HEK293T	FACS;surface expression	NNN PCR	Illumina	No	PDF (Counts)	
32238226	10.1099/mgen.0.000364		Andrews	2020	DMS	LamB	1341		413	phage	E.coli	Growth	error prone pcr	Illumina	PRJNA604031	XLS	urn:mavedb:00000064
32385156	10.1073/pnas.1918680117		Mehlhoff	2020	DMS	TEM-1 BL			5428	E. coli	E.coli	Growth	NNN PCR	Illumina	PRJNA565437	XLS	
32424071	10.1101/gr.260182.119		Kuo	2020	DMS	Shine-Dalgarno sequence			262144	E. Coli	E. Coli						
32510322	10.7554/eLife.56707		Chen	2020	DMS	VIM-2 lactamase	804		5535	E.coli	E.coli	Antibiotics resistance	NNN PCR	Illumina	PRJNA606894	XLS	urn:mavedb:00000073
32522694	10.1016/j.hrthm.2020.05.041		Kozek	2020	DMS	KCNH2			220	Human	HEK293T	Trafficking					
32531152	10.1021/acssynbio.0c00236		Nikoomanzar	2020	DMS	Kod DNA polymerase			7657		E. Coli						
32541028	10.1073/pnas.1920662117		Sharma	2020	DMS	237-CAR			1024	Human T Cells							
32554590	10.1126/science.aaz5143	10.1101/2019.12.30.891135	Wu	2020	DMS	HA			6381	Influenza	Influenza	Growth	NNS/NNK PCR	Illumina	PRJNA510654;PRJNA493101;PRJNA510700	TXT	
32559251	10.1371/journal.ppat.1008647		Park	2020	DMS	PDGFRA			3780	Human		Binding					
32626892	10.1093/protein/gzaa012		Atkinson	2019	DMS	AK						Growth					
32698006	10.1016/j.celrep.2020.107928		Jalal	2020	DMS	ParB			100000								
32701056	10.7554/eLife.53476		Thompson	2020	DMS	DHFR	480			e. coli	E.coli	Growth	NNS PCR	Illumina	?	CSV	urn:mavedb:00000063
32703877	10.1126/science.aba3304	10.1101/2020.04.01.020487	Russ	2020	DMS	CM1			1130		E.coli	Growth	oligo synthesis	Illumina			
32747536	10.1073/pnas.1909634117		Walker	2020	DMS	23S rRNA				E. coli SQZ10	E.coli	Growth	?	Illumina (barcoded)	PRJNA511591	No	
32753553	10.1126/science.abc0870	10.1101/2020.03.16.994236	Chan	2020	DMS	ACE2	2415		2340	human	Expi293F	FACS;Binding	NNK PCR	Illumina	GSE147194	XLS	urn:mavedb:00000069
32786289	10.1021/acschembio.0c00339	10.1101/2020.05.01.072884	Newberry	2020	DMS	alpha-synuclein	423		2600	human	Yeast	Compound resistance	Provided	Illumina (barcoded)	PRJNA56480	XLS	urn:mavedb:00000045
32841599	10.1016/j.cell.2020.08.012	10.1101/2020.06.17.157982	Starr	2020	DMS	SARS-CoV-2 spike	603		3804	SARS CoV 2	yeast	Yeast display	NNS PCR	Illumina	PRJNA639956	TXT	urn:mavedb:00000044
32870157	10.7554/eLife.58026      		Chiasson	2020	DMS	VKOR	489		2695	human	HEK293T	VAMP-seq	Mutagenesis primer	Illumina (barcoded)	GSE149922	CSV	urn:mavedb:00000078
32871012	10.1093/molbev/msaa211		Cote-Hammarlof 	2021	DMS	HSP90			2300	Yeast	Yeast	Growth	NNN PCR	Barcoded Illumina	PRJNA656157	XLS	
32930662	10.7554/eLife.59988		Tenthorey	2020	DMS	Human and Rhesus TRIM5α v1 Loop			231	Human	CRFK	Viral restriction by FACS	NNS PCR	Illumina	No?	CSV	
33084570	10.7554/eLife.54895	10.1101/623108	Jones	2020	DMS	ADRB2	1236		7800		HEK293T	Receptor activity	oligo synthesis	Illumina (barcoded)	No (preprint)	TSV	
33085662	10.1371/journal.pgen.1009009		Zhang	2020	DMS	HIV-1 protease			2736	HIV-1							
33202260	10.1016/j.ajhg.2020.10.015		Meitlis	2020	DMS	CARD11	429		2580	Human	TMD8	Growth	Oligo synthesis	Illumina			
33259788	10.1016/j.chom.2020.11.007		Greaney	2021	DMS	Spike			3804	SARS-CoV-2	Yeast	Antibody binding;FACS	NNS PCR	Illumina	PRJNA639956	CSV (GitHub)	
33326746	10.1016/j.cell.2020.11.024	10.1101/2020.09.09.288324	Tycko	2020	DMS	transcriptional domains			5731	Human							
33340452	10.1016/j.cels.2020.11.012	10.1101/2020.06.22.165571	Aditham	2021	DMS	PHO4			210	Yeast	Yeast	TF expression;DNA binding	QuikChange site-directed mutagenesis	Illumina	10.17605/OSF.IO/8QRZP	No	
33357406	10.1016/j.ajhg.2020.12.003	10.1101/2020.06.03.133017v2	Jia	2021	DMS	MSH2	2805		17746	human	HAP1	Growth		Illumina	GSE162130	MaveDB	urn:mavedb:00000050
33432927	10.7554/eLife.64256		Mattenberger	2021	DMS	Capsid			14839								
33522485	10.7554/eLife.63364		Seuma	2021	DMS	APP			14483								
33524037	10.1371/journal.pgen.1009353	10.1101/2020.06.06.130575	Soo	2021	DMS												
33574611	10.1038/s41587-020-00793-4		Bryant	2021	DMS	AAV2 capsid			201426	AAV	AAV	Growth					
33620761	10.1002/prot.26067	10.1101/2020.06.26.174375	Nedrud	2020	DMS	PSD95 PDZ	249		520743	human	E.coli	Binding	oligo synthesis	Illumina	PRJNA642160	MaveDB	urn:mavedb:00000053
33658230	10.1124/dmd.120.000264		Zhang	2021	DMS	SLCO1B1			137	Human	HEK293T						
33846332	10.1038/s41467-021-22489-2	10.1101/840884	Liu	2021				920									
33847559	10.7554/eLife.66181		Subramanian	2021	DMS	Polymerase cliding clamp and clamp loader			6015;4278;3492	T4 bacteriophage	Phage	Growth					
34157285	10.1016/j.jbc.2021.100900		Trenker	2021	DMS	CD86	78		520	Human	HeLa	Flow Cytometry	NNN PCR	Illumina			
34157285	10.1016/j.jbc.2021.100900 		Trenker	2021	DMS	MARCH1; MIR2	81										urn:mavedb:00000046
34214447	10.1016/j.ajhg.2021.05.009		Weile	2021	DMS	MTHFR	1971		13776	human	Yeast	Growth	popcode	Illumina			urn:mavedb:00000049
34314704	10.1016/j.ajhg.2021.07.001		Amorosi	2021	DMS	CYP2C9	1470		6370	Human	Yeast and HEK293T	Click-seq and VAMP-seq					urn:mavedb:00000095
34408246	10.1038/s42003-021-02490-7		Hamborg	2021	DMS	chymotrypsin inhibitor 2			25	Barley	E.coli	Stability	mutagenic PCR	Illumina	No	No	
34431656	10.1021/acschembio.1c00423	10.1101/2020.08.21.261578	Koberstein	2021	DMS	biosensors			2304								
34491198	10.7554/eLife.71393		Phillips	2021	DMS	bnAbs			65536;2048	Human	Yeast	Binding					
34497069	10.1261/rna.078954.121		Mouali	2021	DMS	ProQ			5000	Salmonella	Salmonella	Growth					
34552126	10.1038/s41598-021-97871-7		Huttinger	2021	DMS	PAI-1			1963	Human	Phage	Binding	error-prone PCR	Illumina	No	TXT	
34638709	10.3390/ijms221910359		Ortiz	2021	DMS	HokC			1616	E.coli	E.coli	Growth				pdf	
34649609	10.1186/s13073-021-00984-x		Matreyek	2021	DMS	PTEN	1212		4112	Human	HEK293T	VAMP-seq				TSV	urn:mavedb:00000101;urn:mavedb:00000102
34756884	10.1016/j.jbc.2021.101359		McKee	2021	DMS	Rhodopsin			700	Human	HEK293T	Plasma membrane expression			No	PDF	
34871407	10.1093/nar/gkab1172	10.1101/2021.03.11.435011	Carmody	2021	DMS	−1PRF			4530								
34919820	10.1016/j.molcel.2021.11.024	10.1101/2021.03.30.437622	Javanmardi	2021	DMS	Spike			200	SARS-CoV-2	HEK293T						
35013287	10.1038/s41420-021-00799-0		Roychowdury	2022	DMS	CASP3;CASP7			1644; 1772			Activity			PRJNA622561	No	
35044296	10.7554/eLife.75555	10.1101/2020.09.08.288233	Katrekar	2022	DMS	ADAR2			4958	Human	HEK293FT	RNA editing activity	Oligonucleotide chip synthesis	Illumina	GSE158656 	No;but raw RNA edits are stored in .gz in GSE15856	
35058622	10.1038/s41587-021-01160-7	10.1101/2020.11.16.383307	Ursu	2022	DMS	KRAS;TP53			200	Human	A549	Perturb-seq	Twist 'clonal gene' platform	Illumina	GSE161824	CSV	
35120642	10.1016/j.cels.2022.01.002	10.1101/2020.10.28.359026	Staller	2022	DMS	7 transcriptional activation domains within VP16;CITED2;HIF1A;P65;STAT3;P53 (2)			3516	Human	K562	FACS	site-directed mutagenesis	Illumina	GSE190288	CSV	
35196514	10.1016/j.ajhg.2022.01.019		Adamovich	2022	DMS	BRACA1-BRCT			2271	Human	HeLa	Growth;Drug Resistance	NNK PCR	Illumina (barcoded)			
35510622	10.7554/eLife.75842	10.1101/2021.12.08.471728	Gonzalez Somermeyer	2021	DMS	GFP		140860		Aequorea victoria	E.coli	Fluorescence	error prone PCR				
35639599	10.7554/eLife.76903	10.1101/2022.01.06.475280	Coyote-Maestas	2022	DMS	Kir2.1	1305		6898;6944	Human	HEK293T	FACS	targeted domain insertion	Illumina	PRJNA791691	CSV (GitHub)	
35688148	10.1016/j.ajhg.2022.05.003	10.1101/2021.07.10.451881	Ng	2021	DMS	KCNH2			1603;458	Human	HEK293T	Trafficking;Patch clamp	QuikChange Lightning multi site-directed mutagenesis	Illumina	dryad.zpc866t9x (patch clamp);dryad.dbrv15f3f (trafficking)	XLSX (patch clamp)	
35723575	10.7554/eLife.77433 	10.1101/2022.01.26.477860	Flynn	2022	DMS	Mpro			6042	SARS-CoV-2	Yeast	FRET + FACS;Fluorescence;Growth	massively parallel oligo synthesis	Illumina	PRJNA842255 	XLSX	
unpublished	unpublished	10.1101/2020.10.14.338756	Heyne	2020	DMS	BPTI			30651								
unpublished	unpublished	10.1101/2021.04.16.440236	Sinai	2021	DMS	AAV2 capsid			22704	AAV	AAV	Growth					
unpublished	unpublished	10.1101/2021.04.19.440442	Young	2021	DMS	SERT			12000		Expi293F	Fluorescence	NNN PCR				
unpublished	unpublished	10.1101/2021.06.06.447205	Trivedi	2021	DMS	PAL				Anabaena variabilis		Activity					
unpublished	unpublished	10.1101/2021.08.21.457204	Stadelmann	2021	DMS	AcrIIA4;AcrIIA5			1740;2800		E.coli						
unpublished	unpublished	10.1101/2021.09.14.460249	Faure	2021	DMS	PSD95-PDZ3 domain;GRB2-SH3 domain			607571		Yeast	Growth	NNN PCR			txt	
unpublished	unpublished	10.1101/2021.10.01.462730	Meier	2021	DMS	EfrCD			1500								
unpublished	unpublished	10.1101/2021.10.06.463360	Silverstein	2021	DMS	GDI1	1344				Yeast	Growth	popcode	Illumina			urn:mavedb:00000066
unpublished	unpublished	10.1101/2021.10.07.463098	Ding	2021	DMS	toxin-antitoxin complex			5796		E.coli	Growth					
unpublished	unpublished	10.1101/2021.12.07.471580	Taft	2021	DMS	Spike				SARS-CoV-2							
unpublished	unpublished	10.1101/2022.03.29.486051	Coelho	2022	DMS	JAK1	3462		10595		HT-29 and LS-411N CRC	Growth		Illumina			
unpublished	unpublished	10.1101/2022.05.04.490571	Gersing	2022	DMS	GCK	1395		9003	Human	Yeast	Growth	NNK PCR	Illumina			
unpublished	unpublished	10.1101/2022.06.10.22276179	Radford	2022	DMS	DDX3X	1986		6766;1886	Human	HAP1	Growth	oligo synthesis	Illumina		No	
unpublished	unpublished	10.1101/2022.12.06.519132v3	Tsuboyama	2022	DMS	synthetic and natural proteins (many)			850000								
unpublished	unpublished	10.1101/831503	Mavor	2019	DMS	Ubiquitin			1520	Yeast	Yeast	Growth	NNN PCR	Illumina (barcoded)			
unpublished	unpublished	unpublished			DMS	HMGCR	2667				Yeast	Growth	popcode	Illumina			urn:mavedb:00000035
unpublished	unpublished	unpublished			DMS	LDLRAP1	927				Hap1	FACS	popcode	Illumina			urn:mavedb:00000036
unpublished	unpublished	unpublished			DMS	NCS1	573				Yeast	Growth	popcode	Illumina			urn:mavedb:00000065
unpublished	unpublished	unpublished			DMS	TECR	927				Yeast	Growth	popcode	Illumina			urn:mavedb:00000067